679398-35-7

Basic information

• Product Name: Benzenamine, 2-[(3Z)-10-[(tetrahydro-2H-pyran-2-yl)oxy]-3-decene-1,5-diynyl]-
• CAS NO: 679398-35-7
• Molecular Formula: C21H25NO2
• Molecular Weight: 323.435
• Mol File: 679398-35-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzenamine, 2-[(3Z)-10-[(tetrahydro-2H-pyran-2-yl)oxy]-3-decene-1,5-diynyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, 2-[(3Z)-10-[(tetrahydro-2H-pyran-2-yl)oxy]-3-decene-1,5-diynyl]-(679398-35-7)
• EPA Substance Registry System: Benzenamine, 2-[(3Z)-10-[(tetrahydro-2H-pyran-2-yl)oxy]-3-decene-1,5-diynyl]-(679398-35-7)

Safety Data

• Hazardous Substances Data: 679398-35-7(Hazardous Substances Data)

Upstream product

• 615-43-0 2-iodophenylamine 
• 1720-37-2 2-(hex-5-yn-1-yloxy)tetrahydro-2H-pyran 
• 888704-55-0 2-((Z)-8-Chloro-oct-7-en-5-ynyloxy)-tetrahydro-pyran 

Downstream Products

• 679398-56-2 N-{2-[10-(tetrahydro-pyran-2-yloxy)-dec-3-ene-1,5-diynyl]-phenyl}-acetamide 

Relevant articles and documents

Synthesis of Carbazoles via an Intramolecular Cyclization of 2-(6-Substituted 3(Z)-hexen,5-diynyl)anilines and Their Related Molecules

Various 2-(6-substituted 3(Z)-hexen-1,5-diynyl)anilines 1a-g were treated with potassium tert-butoxide or potassium 3-ethylpentanoxide in NMP at 60°C for 2 h to give the corresponding 5-substituted carbazoles 2a-g in 36-65% yields together with indoles 9a-g in 21-40% yields, respectively. Exposing the trifluoroacetamide analogues 10h-k under the same reaction conditions gave the carbazoles 2b-e in 37-57% yields and indoles 9b-e in 15-27% yields. Subsequent cyclizations of acetamide analogues 10a-g gave carbazoles 2a-g in 53-86% yields.