67483-13-0 Usage
Description
DIDS, or 4,4'-Diisothiocyanostilbene-2,2'-disulfonic acid, is a stilbene disulfonate that acts as an anion transport inhibitor. It is a yellow to yellow-green or brown powder and exhibits fluorescence with a maximum absorption wavelength of 341 nm and a maximum emission wavelength of 415 nm in water.
Uses
Used in Pharmaceutical Industry:
DIDS is used as an ATP transport inhibitor and anion transport inhibitor for studying the effects of inhibiting anionic transport on various cellular processes.
Used in Medical Research:
DIDS is used as a complexing agent for potassium ions, which can help in understanding the role of potassium in biological systems.
Used in Antiviral Applications:
DIDS reacts with the CD4 glycoprotein on T helper lymphocytes and macrophages, blocking HIV type-1 growth at multiple stages of the viral life cycle.
Used in Gastrointestinal Applications:
DIDS is used as an antiulcer agent, potentially helping in the treatment and management of ulcers in the gastrointestinal tract.
Used in Chloride Transport Studies:
DIDS is used to inhibit Cluptake through plasma membrane-localized Clchannels, allowing researchers to study chloride transport and its role in various physiological processes.
Used in Sodium-coupled Bicarbonate Transporter Inhibition:
DIDS effectively inhibits various sodium-coupled bicarbonate transporters, which can be useful in studying the regulation of bicarbonate transport and its implications in acid-base balance and other physiological functions.
Check Digit Verification of cas no
The CAS Registry Mumber 67483-13-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,7,4,8 and 3 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 67483-13:
(7*6)+(6*7)+(5*4)+(4*8)+(3*3)+(2*1)+(1*3)=150
150 % 10 = 0
So 67483-13-0 is a valid CAS Registry Number.
