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  • 6746-81-2 Structure
  • Basic information

    1. Product Name: GLYCIDYL 4-TOLUENESULFONATE
    2. Synonyms: TOLUENE-4-SULFONIC ACID OXIRANYLMETHYL ESTER;GLYCIDYL 4-TOLUENESULFONATE;2,3-Epoxypropyl p-toluenesulfonate;5-Methyl-2-(oxiran-2-ylMethyl)benzene-1-sulfonate;OxiraneMethanol, 4-Methylbenzenesulfonate;2-Oxiranemethanol,2-(4-methylbenzenesulfonate)
    3. CAS NO:6746-81-2
    4. Molecular Formula: C10H12O4S
    5. Molecular Weight: 228.26
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 6746-81-2.mol
    9. Article Data: 30
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 95-100 °C(Press: 0.01 Torr)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.310±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: -20°C Freezer, Under inert atmosphere
    8. Solubility: Chloroform (Sparingly), Methanol (Slightly)
    9. CAS DataBase Reference: GLYCIDYL 4-TOLUENESULFONATE(CAS DataBase Reference)
    10. NIST Chemistry Reference: GLYCIDYL 4-TOLUENESULFONATE(6746-81-2)
    11. EPA Substance Registry System: GLYCIDYL 4-TOLUENESULFONATE(6746-81-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 6746-81-2(Hazardous Substances Data)

6746-81-2 Usage

Description

GLYCIDYL 4-TOLUENESULFONATE, also known as GTS, is an organic compound that serves as a reagent in various chemical reactions. It is characterized by its ability to participate in organic displacement, addition, and ring-opening reactions, making it a versatile compound in the field of chemistry.

Uses

Used in Pharmaceutical Industry:
GLYCIDYL 4-TOLUENESULFONATE is used as a reagent for the development and validation of a chiral HPLC (High-Performance Liquid Chromatography) method. This method is crucial for rapid screening of allylic alcohol asymmetric epoxidation processes, which are essential in the synthesis of various pharmaceutical compounds. GLYCIDYL 4-TOLUENESULFONATE's role in these processes aids in the efficient and accurate analysis of the reactions, contributing to the advancement of drug development.
Used in Chemical Synthesis:
GLYCIDYL 4-TOLUENESULFONATE is used as a reagent in organic displacement, addition, and ring-opening reactions. Its versatility in these reactions makes it a valuable tool in the synthesis of various organic compounds, including those used in the production of pharmaceuticals, agrochemicals, and other specialty chemicals. GLYCIDYL 4-TOLUENESULFONATE's ability to participate in these reactions allows for the creation of new molecules with specific properties, expanding the possibilities in chemical research and development.

Check Digit Verification of cas no

The CAS Registry Mumber 6746-81-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,7,4 and 6 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 6746-81:
(6*6)+(5*7)+(4*4)+(3*6)+(2*8)+(1*1)=122
122 % 10 = 2
So 6746-81-2 is a valid CAS Registry Number.

6746-81-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name oxiran-2-ylmethyl 4-methylbenzenesulfonate

1.2 Other means of identification

Product number -
Other names (2S)-Glycidyl tosylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6746-81-2 SDS

6746-81-2Relevant articles and documents

An Unexpected Transannular [4+2] Cycloaddition during the Total Synthesis of (+)-Norcembrene 5

Breunig, Michael,Gaich, Tanja,Yuan, Po

supporting information, p. 5521 - 5525 (2020/02/20)

We report a concise and versatile total synthesis of the diterpenoid (+)-norcembrene 5 from simple building blocks. Ring-closing metathesis and an auxiliary-directed 1,4-addition are the key steps of our synthetic route. During the synthesis, an unprecede

Dihydroquinozinone carboxylic acid compound and application thereof (by machine translation)

-

Paragraph 0078-0081, (2020/02/14)

The invention belongs to the field of, pharmaceutical chemistry, and relates to (HBV) a dihydroquinozinone carboxylic acid compound with the activity of, and resisting hepatitis B virus (hepatitis B virus) .and a preparation method of the dihydroquinozino

Glycidyl Tosylate: Polymerization of a “Non-Polymerizable” Monomer permits Universal Post-Functionalization of Polyethers

Jung, Philipp,Ziegler, Arthur D.,Blankenburg, Jan,Frey, Holger

supporting information, p. 12883 - 12886 (2019/08/22)

Glycidyl tosylate appears to be a non-polymerizable epoxide when nucleophilic initiators are used because of the excellent leaving group properties of the tosylate. However, using the monomer-activated mechanism, this unusual monomer can be copolymerized

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