66753-05-7 Usage
Description
ARACHIDONIC ACID, [5,6,8,9,11,12,14,15-3H(N)]is a polyunsaturated omega-6 fatty acid with the chemical formula C20H32O2. It is labeled with tritium at multiple positions, making it suitable for radioligand binding studies and metabolic research. ARACHIDONIC ACID, [5,6,8,9,11,12,14,15-3H(N)]is a key component of cell membranes and serves as a precursor for the synthesis of eicosanoids, which are potent lipid mediators involved in inflammation, pain, and fever. It is naturally present in various foods such as meat, eggs, and dairy products, and can also be produced in the body from linoleic acid. Furthermore, arachidonic acid has been implicated in various diseases and conditions, including cardiovascular diseases, arthritis, and cancer.
Uses
Used in Pharmaceutical Industry:
ARACHIDONIC ACID, [5,6,8,9,11,12,14,15-3H(N)]is used as a radiolabeled compound for radioligand binding studies and metabolic research. Its radiolabeled nature allows researchers to track its distribution, metabolism, and mechanism of action within the body, which can help in the development of new drugs and therapies targeting inflammation and immune response.
Used in Nutritional Research:
ARACHIDONIC ACID, [5,6,8,9,11,12,14,15-3H(N)]is used as a tracer in nutritional studies to investigate the role of omega-6 fatty acids in the body. This can help researchers understand the balance between omega-3 and omega-6 fatty acids and their impact on health and disease.
Used in Disease Research:
ARACHIDONIC ACID, [5,6,8,9,11,12,14,15-3H(N)]is used as a research tool to study its involvement in various diseases and conditions, such as cardiovascular diseases, arthritis, and cancer. Understanding its role in these conditions can aid in the development of targeted therapies and interventions.
Used in Food Industry:
ARACHIDONIC ACID, [5,6,8,9,11,12,14,15-3H(N)]can be used to study the effects of dietary intake of omega-6 fatty acids on health. This can help in the development of food products with optimized fatty acid profiles to promote health and prevent disease.
Check Digit Verification of cas no
The CAS Registry Mumber 66753-05-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,7,5 and 3 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 66753-05:
(7*6)+(6*6)+(5*7)+(4*5)+(3*3)+(2*0)+(1*5)=147
147 % 10 = 7
So 66753-05-7 is a valid CAS Registry Number.
InChI:InChI=1/C20H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-,16-15-/i6T,7T,9T,10T,12T,13T,15T,16T
66753-05-7Relevant articles and documents
Synthesis of tritium labelled arachidonic acid amide and ester derivatives with dopamine, serotonin, vanillylamine, and ethyleneglycol moieties
Shevchenko,Nagaev,Myasoedov,Yudushkin,Gretskaya,Bobrov,Bezuglov
, p. 187 - 193 (2003)
Tritium labelled arachidonic acid amides with dopamine, serotonin, vanillylamine and the ethyleneglycol ester moieties with high specific activity (120 Ci/ mmol) and yield (70-90%) were prepared from tritiated arachidonic acid by condensation with the cor
