66068-38-0

Basic information

• Product Name: 4-NITROPHENYL-ALPHA-D-MALTOPENTAOSIDE
• Synonyms: PG5;PNP-ALPHA-D-MALTOPENTAOSIDE;P-NITROPHENYL-ALPHA-D-PENTA-GLUCOPYRANOSIDE;P-NITROPHENYL-ALPHA-D-MALTOPENTAOSIDE;4-NITROPHENYL-ALPHA-D-MALTOPENTAOSIDE;4-NITROPHENYL-ALPHA-D-PENTA-(1->4)-GLUCOPYRANOSIDE;BG5P;4)-gluco pyranoside
• CAS NO: 66068-38-0
• Molecular Formula: C₃₆H₅₅NO₂₈
• Molecular Weight: 949.81
• Product Categories: substrate
• Mol File: 66068-38-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 1259.2±65.0 °C(Predicted)
• Appearance: /
• Density: 1.81±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 12.43±0.70(Predicted)
• CAS DataBase Reference: 4-NITROPHENYL-ALPHA-D-MALTOPENTAOSIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-NITROPHENYL-ALPHA-D-MALTOPENTAOSIDE(66068-38-0)
• EPA Substance Registry System: 4-NITROPHENYL-ALPHA-D-MALTOPENTAOSIDE(66068-38-0)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36-24/25-22
• WGK Germany: 3
• F: 8-10-21
• Hazardous Substances Data: 66068-38-0(Hazardous Substances Data)

Usage

Description

4-NITROPHENYL-ALPHA-D-MALTOPENTAOSIDE is a synthetic compound that serves as a substrate for the enzyme α-amylase. It is a derivative of maltopentaose, a disaccharide composed of five glucose units, with a 4-nitrophenyl group attached to the reducing end. 4-NITROPHENYL-ALPHA-D-MALTOPENTAOSIDE is widely utilized in the detection and quantification of α-amylase activity due to its unique structure and properties.

Uses

Used in Medical Diagnostics:
4-NITROPHENYL-ALPHA-D-MALTOPENTAOSIDE is used as a diagnostic tool for α-amylase determination in human blood serum and urine. The application reason is that the compound allows for the accurate measurement of α-amylase levels, which can be indicative of various health conditions, such as pancreatitis, diabetes, and other pancreatic or gastrointestinal disorders. By monitoring α-amylase activity, healthcare professionals can assess a patient's health status and make informed decisions regarding diagnosis and treatment.

Upstream product

• 74173-30-1 C₄₂H₆₅NO₃₃ 
• 1668-09-3 Maltopentaose 
• 3767-28-0 4-nitrophenyl-α-D-glucopyranoside 
• 7585-39-9 β‐cyclodextrin 
• 2492-87-7 4-nitrophenyl-β-D-glucoside 

Downstream Products

• 14609-74-6 p-nitrophenolate 
• 129411-66-1 C₆₈H₈₇NO₄₄ 
• 117374-86-4 C₄₃H₅₉NO₂₈ 
• 3482-57-3 p-nitrophenyl-α-D-glucopyranosyl-(1→4)-O-α-D-glucopyranoside 
• 66451-58-9 4-nitrophenyl α-maltotrioside 
• 66068-37-9 4-nitrophenyl α-maltotetraoside 
• 3767-28-0 4-nitrophenyl-α-D-glucopyranoside 

Relevant articles and documents

Acceptor-induced modification of regioselectivity in CGTase-catalyzed glycosylations of p-nitrophenyl-glucopyranosides

Cyclodextrin glycosyltransferases (CGTase) are reported to selectively catalyze α(1→4)-glycosyl transfer reactions besides showing low hydrolytic activity. Here, the effect of the anomeric configuration of the glycosyl acceptor on the regioselectivity of

Maltotetraose-forming, amylase-mediated, p-nitrophenyl α- and β-maltopentaoside formation in an aqueous-organic solvent system: a substrate for human amylase in serum

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