65515-28-8 Usage
Description
METHYL 2,6-DICHLOROPYRIDINE-3-CARBOXYLA& is an organic compound that serves as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. It is characterized by its chlorinated pyridine ring and carboxylate group, which can be further functionalized to produce a range of derivatives with diverse applications.
Uses
Used in Pharmaceutical Industry:
METHYL 2,6-DICHLOROPYRIDINE-3-CARBOXYLA& is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its chlorinated pyridine ring and carboxylate group can be modified to produce a range of active pharmaceutical ingredients with different therapeutic properties.
Used in Agrochemical Industry:
METHYL 2,6-DICHLOROPYRIDINE-3-CARBOXYLA& is also used as a building block in the development of agrochemicals, such as herbicides and insecticides. Its unique chemical structure allows for the creation of compounds with targeted pest control properties, contributing to more effective and environmentally friendly agricultural practices.
Used in Organic Synthesis:
METHYL 2,6-DICHLOROPYRIDINE-3-CARBOXYLA& is utilized as a versatile starting material in organic synthesis, enabling the production of a variety of organic compounds with different functional groups and applications. Its reactivity and stability make it a valuable component in the synthesis of complex organic molecules.
Used in Replacement of Halides:
METHYL 2,6-DICHLOROPYRIDINE-3-CARBOXYLA& is used in the replacement of chlorides with fluorides using anhydrous nucleophilic fluoride salts generated from potassium fluoride and an arene transfer agent. This process allows for the selective substitution of halide groups, enabling the synthesis of novel compounds with improved properties and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 65515-28-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,5,5,1 and 5 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 65515-28:
(7*6)+(6*5)+(5*5)+(4*1)+(3*5)+(2*2)+(1*8)=128
128 % 10 = 8
So 65515-28-8 is a valid CAS Registry Number.
InChI:InChI=1/C7H5Cl2NO2/c1-12-7(11)4-2-3-5(8)10-6(4)9/h2-3H,1H3
65515-28-8Relevant articles and documents
HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS
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Paragraph 0414, (2021/01/23)
Heterocyclic compounds as CDK4 or CDK6 or other CDK inhibitors are provided. The compounds may find use as therapeutic agents for the treatment of diseases and may find particular use in oncology.
BENZO[B][1,8]NAPHTHYRIDINE ACETIC ACID DERIVATIVES AND METHODS OF USE
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Page/Page column 126, (2020/12/01)
Compounds of Formula I or pharmaceutically acceptable salts or esters thereof capable of binding to and modulating the activity of a stimulator of interferon genes (STING) protein are provided. Methods involving compounds of Formula I as effective modulators of STING are also provided.
A scalable and safe continuous flow procedure for in-line generation of diazomethane and its precursor MNU
Lehmann
supporting information, p. 1449 - 1453 (2017/05/10)
Diazomethane is a valuable C1-building block for organic synthesis. Due to its intrinsic reactivity and instability, handling of this reagent is associated with serious safety hazards. Herein we present a simple and robust continuous flow process, allowing a safe and on-demand generation of diazomethane with a productivity of 95-117 mmol h-1. The developed two-step process starts from non-hazardous N-methylurea, and generates and consumes N-methyl-N-nitrosourea (MNU) and diazomethane, thus enabling a safe and convenient scale-up to a multi-gram scale in a conventional synthesis laboratory.
