65134-44-3

Basic information

• Product Name: 2-Propenenitrile, 3-phenoxy-3-phenyl-, (Z)-
• CAS NO: 65134-44-3
• Molecular Formula: C15H11NO
• Molecular Weight: 221.258
• Mol File: 65134-44-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Propenenitrile, 3-phenoxy-3-phenyl-, (Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenenitrile, 3-phenoxy-3-phenyl-, (Z)-(65134-44-3)
• EPA Substance Registry System: 2-Propenenitrile, 3-phenoxy-3-phenyl-, (Z)-(65134-44-3)

Safety Data

• Hazardous Substances Data: 65134-44-3(Hazardous Substances Data)

Upstream product

• 536-74-3 phenylacetylene 
• 935-02-4 3-Phenyl-2-propynonitrile 
• 108-95-2 phenol 
• 139-02-6 sodium phenoxide 

Downstream Products

• 37883-72-0 2-phenylbenzo[b]furan-3-carbonitrile 
• 872276-59-0 β-ethoxy-cinnamonitrile 
• 7664-41-7 ammonia 
• 98-86-2 acetophenone 
• 108-95-2 phenol 

Relevant articles and documents

Copper-catalyzed direct cyanation of terminal alkynes with benzoyl cyanide

Copper-catalyzed direct cyanation of terminal alkynes is achieved using less toxic, stable and easy to handle benzoyl cyanide as a cyanide source and air as an oxidant. This protocol provides a good alternative to the preparation of 3-arylpropiolonitriles

Synthesis of (Z)-3-aryloxy-acrylonitriles, (E)-3-aryloxy-acrylonitriles and 3-cyanobenzofurans through the sequential reactions of phenols with propiolonitriles

A Na2CO3-promoted addition of phenols to propiolonitriles generated (Z)-3-aryloxy-acrylonitriles in nearly quantitative yields with exclusively Z-isomers, and a DABCO-promoted addition reaction of phenols with propiolonitriles afforded mainly (E)-3-aryloxy-acrylonitriles with high yields. The obtained (E)-3-aryloxy-acrylonitriles underwent intramolecular cyclization to give 3-cyanobenzofurans in good yields through palladium-catalyzed direct C-H bond functionalization.