64987-05-9

Basic information

• Product Name: Ethyl 2-formamidothiazol-4-acetate
• Synonyms: EFTA:ETHYL 2-(2-FORMYLAMINOTHIAZOL-4-YL) ACETATE;EFATA;2-(Formylamino)-4-thiazoleacetic acid ethyl ester;2-(Formylamino)thiazole-4-acetic acid ethyl ester;Ethyl 2-(2-forMaMidothiazol-4-yl)acetate;ethyl2-(formylamino)-4-thiazoleacetate;4-THIAZOLEACETIC ACID, 2-(FORMYLAMINO)-, ETHYL ESTER;Ethyl 2-(2-formamido-1,3-thiazol-4-yl)acetate
• CAS NO: 64987-05-9
• Molecular Formula: C₈H₁₀N₂O₃S
• Molecular Weight: 214.24
• EINECS: 265-300-8
• Product Categories: Pharmaceutical Intermediates
• Mol File: 64987-05-9.mol
• Article Data: 6

Chemical Properties

• Melting Point: 130-132 °C(lit.)
• Boiling Point: 341.4 °C at 760 mmHg
• Flash Point: 160.3 °C
• Appearance: /
• Density: 1.354 g/cm³
• Vapor Pressure: 8.07E-05mmHg at 25°C
• Refractive Index: 1.586
• Storage Temp.: 2-8°C
• PKA: 8.53±0.70(Predicted)
• CAS DataBase Reference: Ethyl 2-formamidothiazol-4-acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 2-formamidothiazol-4-acetate(64987-05-9)
• EPA Substance Registry System: Ethyl 2-formamidothiazol-4-acetate(64987-05-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• Hazardous Substances Data: 64987-05-9(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
Ethyl 2-formamidothiazol-4-acetate is used as a reagent for the synthesis of aryl glyoxylates. It plays a crucial role in the preparation of these compounds, which are important intermediates in the synthesis of various organic molecules, including pharmaceuticals and agrochemicals.
In the pharmaceutical industry, aryl glyoxylates can be used as key intermediates in the synthesis of drugs with diverse therapeutic applications. Ethyl 2-formamidothiazol-4-acetate, as a reagent in their production, contributes to the development of new and effective medications.
In the agrochemical industry, aryl glyoxylates can be utilized in the synthesis of pesticides and other crop protection agents. The use of Ethyl 2-formamidothiazol-4-acetate in this context aids in the creation of more effective and environmentally friendly products for agricultural use.
Overall, Ethyl 2-formamidothiazol-4-acetate is a valuable reagent in the synthesis of aryl glyoxylates, which have wide-ranging applications in both the pharmaceutical and agrochemical industries, contributing to the development of new and improved products.

InChI:InChI=1/C8H10N2O3S/c1-2-13-7(12)3-6-4-14-8(10-6)9-5-11/h4-5H,2-3H2,1H3,(H,9,10,11)

Upstream product

• 53266-94-7 ethyl 2-amino-1,3-thiazol-4-acetate 
• 2258-42-6 formyl acetic anhydride 

Downstream Products

• 64987-03-7 ethyl 2-(2-formylaminothiazol-4-yl)glyoxylate 
• 64987-06-0 2-(2-formylamino-1,3-thiazol-4-yl)glyoxylic acid 

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