6490-08-0

Basic information

• Product Name: (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-(2-phenyl-2-{[1-phenyl-meth-(E)-ylidene]-amino}-acetylamino)-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid
• CAS NO: 6490-08-0
• Molecular Weight: 437.519
• Mol File: 6490-08-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-(2-phenyl-2-{[1-phenyl-meth-(E)-ylidene]-amino}-acetylamino)-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-(2-phenyl-2-{[1-phenyl-meth-(E)-ylidene]-amino}-acetylamino)-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid(6490-08-0)
• EPA Substance Registry System: (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-(2-phenyl-2-{[1-phenyl-meth-(E)-ylidene]-amino}-acetylamino)-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid(6490-08-0)

Safety Data

• Hazardous Substances Data: 6490-08-0(Hazardous Substances Data)

Upstream product

• 96606-98-3 (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-(2-phenyl-2-{[1-phenyl-meth-(E)-ylidene]-amino}-acetylamino)-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid 1-ethoxycarbonyloxy-ethyl ester 
• 107-45-9 tert-Octylamine 
• 100-52-7 benzaldehyde 
• 53059-77-1 6β-(4-methoxy-benzylideneamino)-penicillanic acid 
• 3412-49-5 N-carboxy-(R)-phenylglycine anhydride 
• 69-53-4 ampicillin 

Downstream Products

• 203127-11-1 (2S,5R,6R)-6-((R)-2-Amino-2-phenyl-acetylamino)-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid 3-cyclohexylidene-2,5-dioxo-pyrrolidin-1-ylmethyl ester 
• 33993-48-5 ampicillin 

Relevant articles and documents

Ester prodrugs of ampicillin tailored for intracellular accumulation

Seven new ester prodrugs of ampicillin with hydrolysis half-lives ranging from 65 to 308 min were synthesized. The cellular accumulation of two of them (in J774 mouse macrophages) and their activities against intracellular Staphylococcus aureus were determined in comparison with the pivaloyloxymethylester of ampicillin (pivampicillin) and ampicillin. The esters accumulated extensively and were more active than ampicillin in this in vitro system.