64488-52-4 Usage
Description
N-[4-(2-Chloroacetyl)phenyl]methanesulfonamide is an organic compound that serves as a key building block in the synthesis of a wide range of chemical compounds. Its unique structure, which includes a chloroacetyl group attached to a phenyl ring and a methanesulfonamide group, allows for versatile chemical reactions and modifications, making it a valuable component in the development of new molecules with various applications.
Uses
Used in Pharmaceutical Industry:
N-[4-(2-Chloroacetyl)phenyl]methanesulfonamide is used as a synthetic intermediate for the development of new pharmaceutical compounds. Its reactivity and structural diversity enable the creation of novel drugs with potential applications in treating various diseases and medical conditions.
Used in Chemical Research:
In the field of chemical research, N-[4-(2-Chloroacetyl)phenyl]methanesulfonamide is utilized as a starting material for the synthesis of complex organic molecules. Its unique functional groups facilitate various chemical reactions, allowing researchers to explore new pathways and develop innovative compounds with potential applications in various industries.
Used in Material Science:
N-[4-(2-Chloroacetyl)phenyl]methanesulfonamide can also be employed in the development of new materials with specific properties. Its structural characteristics make it a suitable candidate for the synthesis of advanced materials, such as polymers, coatings, and adhesives, which can be used in various applications, including automotive, aerospace, and electronics industries.
Check Digit Verification of cas no
The CAS Registry Mumber 64488-52-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,4,8 and 8 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 64488-52:
(7*6)+(6*4)+(5*4)+(4*8)+(3*8)+(2*5)+(1*2)=154
154 % 10 = 4
So 64488-52-4 is a valid CAS Registry Number.
InChI:InChI=1/C9H10ClNO3S/c1-15(13,14)11-8-4-2-7(3-5-8)9(12)6-10/h2-5,11H,6H2,1H3
64488-52-4Relevant articles and documents
Chemoenzymatic synthesis of (S) and (R)-propranolol and sotalol employing one-pot lipase resolution protocol
Kamal, Ahmed,Sandbhor, Mahendra,Ali Shaik, Ahmad
, p. 4581 - 4583 (2007/10/03)
Synthesis of both enantiomers of biologically active propranolol and sotalol has been achieved in high optical purity by one-pot reduction of 3 and 7 followed by in situ lipase resolution of the respective chlorohydrins. Pseudomonas cepacia lipase immobilized on ceramic particles (PS-C) provided the chlorohydrin and acetate, which on nucleophilic substitution with isopropyl amine afforded the target amino alcohols in high enantioselectivity under mild reaction conditions.
Synthesis and Antiarrhythmic Activity of Novel 3-Alkyl-1-phenyl>-ω-hydroxyalkyl>-1H-imidazolium Salts and Related Compounds
Lis, Randall,Morgan, Thomas K.,DeVita, Robert J.,Davey, David D.,Lumma, William C.,et al.
, p. 696 - 704 (2007/10/02)
Novel 3-alkyl-1-phenyl>-ω-hydroxyalkyl>-1H-imidazolium salts were synthesized and investigated for their class III electrophysiological activity on isolated canine cardiac Purkinje fibers and ventricular muscle tissue.Structure-activity relationships are discussed for a series of 25 compounds.Compound 3, 1-phenyl>ethyl>-3-methyl-1H-imidazolium chloride, prolonged the functional refractory period in anesthetized dogs when given intraduodenally and was also effective in preventing reentrant ventricular tachycardia induced by programmed electrical stimulation when administered intravenously in anesthetized dogs 24 h after an acute myocardial infarction.Both enantiomers of 3 were synthesized.No enantioselectivity was found in the electrophysiological effects of 3.