64325-12-8Relevant articles and documents
Selective Synthesis of Phenolic Mannich Bases under Solid-Liquid Phase Transfer Conditions
Pochini, Andrea,Puglia, Giuseppe,Ungaro, Rocco
, p. 906 - 907 (1983)
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SELECTIVE FUNCTIONALIZATION OF AROMATIC COMPOUNDS. I. ORTHO-AMINOALKYLATION OF PHENOL AND o-tert-BUTYLPHENOL
Salakhutdinov, N. F.,Krysin, A. P.,Koptyug, V. A.
, p. 664 - 665 (2007/10/02)
The aminomethylation of phenol in a complex with β-cyclodextrin, formalin, and dialkylamine gives the mono-ortho-aminoalkyl derivative.In contrast to this, for o-tert-butylphenol selective ortho-aminoalkylation can be realized without complex formation under the normal conditions of the Mannich reaction.