Welcome to LookChem.com Sign In|Join Free

CAS

  • or
Octanedial, also known as 1,8-octanedial, is a colorless liquid chemical compound with the formula C8H14O2. It is characterized by a pungent, fruity odor and is found in natural food sources such as black tea, coffee, peach, and beer. Primarily used as a flavoring agent in the food industry, Octanedial also serves as a chemical intermediate in the production of pharmaceuticals and other organic compounds. While considered relatively safe for use in food and consumer products, it requires careful handling to prevent skin and eye irritation.

638-54-0 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 638-54-0 Structure
  • Basic information

    1. Product Name: octanedial
    2. Synonyms: octanedial;1,6-Hexanedicarbaldehyde;Octadinal;Suberic aldehyde
    3. CAS NO:638-54-0
    4. Molecular Formula: C8H14O2
    5. Molecular Weight: 142.19556
    6. EINECS: 211-342-7
    7. Product Categories: N/A
    8. Mol File: 638-54-0.mol
    9. Article Data: 72
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 199.78°C (rough estimate)
    3. Flash Point: 81 °C
    4. Appearance: /
    5. Density: 0.9695 (rough estimate)
    6. Vapor Pressure: 0.0942mmHg at 25°C
    7. Refractive Index: 1.4439 (estimate)
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: octanedial(CAS DataBase Reference)
    11. NIST Chemistry Reference: octanedial(638-54-0)
    12. EPA Substance Registry System: octanedial(638-54-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 638-54-0(Hazardous Substances Data)

638-54-0 Usage

Uses

Used in Food Industry:
Octanedial is used as a flavoring agent for its distinctive pungent, fruity odor, enhancing the taste and aroma of various food products.
Used in Pharmaceutical Production:
Octanedial is utilized as a chemical intermediate in the synthesis of pharmaceuticals, contributing to the development of new medications and therapeutic agents.
Used in Organic Compound Synthesis:
As a versatile chemical intermediate, Octanedial is employed in the production of various organic compounds, expanding its applications across different industries.

Check Digit Verification of cas no

The CAS Registry Mumber 638-54-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,3 and 8 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 638-54:
(5*6)+(4*3)+(3*8)+(2*5)+(1*4)=80
80 % 10 = 0
So 638-54-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H14O2/c9-7-5-3-1-2-4-6-8-10/h7-8H,1-6H2

638-54-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name octanedial

1.2 Other means of identification

Product number -
Other names Octanedial

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:638-54-0 SDS

638-54-0Relevant articles and documents

Selective TEMPO-Oxidation of Alcohols to Aldehydes in Alternative Organic Solvents

Hinzmann, Alessa,Stricker, Michael,Busch, Jasmin,Glinski, Sylvia,Oike, Keiko,Gr?ger, Harald

, p. 2399 - 2408 (2020/04/29)

The TEMPO-catalyzed oxidation of alcohols to aldehydes has emerged to one of the most widely applied methodologies for such transformations. Advantages are the utilization of sodium hypochlorite, a component of household bleach, as an oxidation agent and the use of water as a co-solvent. However, a major drawback of this method is the often occurring strict limitation to use dichloromethane as an organic solvent in a biphasic reaction medium with water. Previous studies show that dichloromethane cannot easily be substituted because a decrease of selectivity or inhibition of the reaction is observed by using alternative organic solvents. Thus, up to now, only a few examples are known in which after a tedious optimization of the reaction dichloromethane could be replaced. In order to overcome the current limitations, we were interested in finding a TEMPO-oxidation method in alternative organic solvents, which is applicable for various alcohol oxidations. As a result, we found a method for N-oxyl radical-catalyzed oxidation using sodium hypochlorite as an oxidation agent in nitriles as an organic solvent component instead of dichloromethane. Besides the oxidation of aromatic primary alcohols also aliphatic primary alcohols, secondary alcohols as well as dialcohols were successfully converted when using this method, showing high selectivity towards the carbonyl compound and low amounts of the acid side-product.

Production of Hydroxy Acids: Selective Double Oxidation of Diols by Flavoprotein Alcohol Oxidase

Fraaije, Marco W.,Martin, Caterina,Trajkovic, Milos

, p. 4869 - 4872 (2020/02/11)

Flavoprotein oxidases can catalyze oxidations of alcohols and amines by merely using molecular oxygen as the oxidant, making this class of enzymes appealing for biocatalysis. The FAD-containing (FAD=flavin adenine dinucleotide) alcohol oxidase from P. chrysosporium facilitated double and triple oxidations for a range of aliphatic diols. Interestingly, depending on the diol substrate, these reactions result in formation of either lactones or hydroxy acids. For example, diethylene glycol could be selectively and fully converted into 2-(2-hydroxyethoxy)acetic acid. Such a facile cofactor-independent biocatalytic route towards hydroxy acids opens up new avenues for the preparation of polyester building blocks.

An Engineered Alcohol Oxidase for the Oxidation of Primary Alcohols

Heath, Rachel S.,Birmingham, William R.,Thompson, Matthew P.,Taglieber, Andreas,Daviet, Laurent,Turner, Nicholas J.

, p. 276 - 281 (2019/01/04)

Structure-guided directed evolution of choline oxidase has been carried out by using the oxidation of hexan-1-ol to hexanal as the target reaction. A six-amino-acid variant was identified with a 20-fold increased kcat compared to that of the wild-type enzyme. This variant enabled the oxidation of 10 mm hexanol to hexanal in less than 24 h with 100 % conversion. Furthermore, this variant showed a marked increase in thermostability with a corresponding increase in Tm of 20 °C. Improved solvent tolerance was demonstrated with organic solvents including ethyl acetate, heptane and cyclohexane, thereby enabling improved conversions to the aldehyde by up to 30 % above conversion for the solvent-free system. Despite the evolution of choline oxidase towards hexan-1-ol, this new variant also showed increased specific activities (by up to 100-fold) for around 50 primary aliphatic, unsaturated, branched, cyclic, benzylic and halogenated alcohols.

Cis -Oxoruthenium complexes supported by chiral tetradentate amine (N4) ligands for hydrocarbon oxidations

Tse, Chun-Wai,Liu, Yungen,Wai-Shan Chow, Toby,Ma, Chaoqun,Yip, Wing-Ping,Chang, Xiao-Yong,Low, Kam-Hung,Huang, Jie-Sheng,Che, Chi-Ming

, p. 2803 - 2816 (2018/03/21)

We report the first examples of ruthenium complexes cis-[(N4)RuIIICl2]+ and cis-[(N4)RuII(OH2)2]2+ supported by chiral tetradentate amine ligands (N4), together with a high-valent cis-dioxo complex cis-[(N4)RuVI(O)2]2+ supported by the chiral N4 ligand mcp (mcp = N,N′-dimethyl-N,N′-bis(pyridin-2-ylmethyl)cyclohexane-1,2-diamine). The X-ray crystal structures of cis-[(mcp)RuIIICl2](ClO4) (1a), cis-[(Me2mcp)RuIIICl2]ClO4 (2a) and cis-[(pdp)RuIIICl2](ClO4) (3a) (Me2mcp = N,N′-dimethyl-N,N′-bis((6-methylpyridin-2-yl)methyl)cyclohexane-1,2-diamine, pdp = 1,1′-bis(pyridin-2-ylmethyl)-2,2′-bipyrrolidine)) show that the ligands coordinate to the ruthenium centre in a cis-α configuration. In aqueous solutions, proton-coupled electron-transfer redox couples were observed for cis-[(mcp)RuIII(O2CCF3)2]ClO4 (1b) and cis-[(pdp)RuIII(O3SCF3)2]CF3SO3 (3c′). Electrochemical analyses showed that the chemically/electrochemically generated cis-[(mcp)RuVI(O)2]2+ and cis-[(pdp)RuVI(O)2]2+ complexes are strong oxidants with E° = 1.11-1.13 V vs. SCE (at pH 1) and strong H-atom abstractors with DO-H = 90.1-90.8 kcal mol-1. The reaction of 1b or its (R,R)-mcp counterpart with excess (NH4)2[CeIV(NO3)6] (CAN) in aqueous medium afforded cis-[(mcp)RuVI(O)2](ClO4)2 (1e) or cis-[((R,R)-mcp)RuVI(O)2](ClO4)2 (1e?), respectively, a strong oxidant with E(RuVI/V) = 0.78 V (vs. Ag/AgNO3) in acetonitrile solution. Complex 1e oxidized various hydrocarbons, including cyclohexane, in acetonitrile at room temperature, affording alcohols and/or ketones in up to 66% yield. Stoichiometric oxidations of alkenes by 1e or 1e? in tBuOH/H2O (5:1 v/v) afforded diols and aldehydes in combined yields of up to 98%, with moderate enantioselectivity obtained for the reaction using 1e?. The cis-[(pdp)RuII(OH2)2]2+ (3c)-catalysed oxidation of saturated C-H bonds, including those of ethane and propane, with CAN as terminal oxidant was also demonstrated.

Oxidation of terminal diols using an oxoammonium salt: A systematic study

Miller, Shelli A.,Bobbitt, James M.,Leadbeater, Nicholas E.

supporting information, p. 2817 - 2822 (2017/04/04)

A systematic study of the oxidation of a range of terminal diols is reported, employing the oxoammonium salt 4-acetamido-2,2,6,6-tetramethylpiperidine-1-oxoammonium tetrafluoroborate (4-NHAc-TEMPO+ BF4-) as the oxidant. For substrates bearing a hydrocarbon chain of seven carbon atoms or more, the sole product is the dialdehyde. A series of post-oxidation reactions have been performed showing that the product mixture resulting from the oxidation step can be taken on directly to a subsequent transformation. For diols containing four to six carbon atoms, the lactone product is the major product upon oxidation. In the case of 1,2-ethanediol and 1,3-propanediol, when using a 1 : 0.5 stoichiometric ratio of substrate to oxidant, the corresponding monoaldehyde is formed which reacts rapidly with further diol to yield the acetal product. This is of particular synthetic value given both the difficulty of their preparation using other approaches and also their potential application in further reaction chemistry.

Preparation method and application of brphinsted acidic ionic liquid using periodate as anion as well as method for preparing alpha,omega-dialdehyde

-

Paragraph 0130; 0131, (2017/05/12)

The invention relates to the field of fine chemical industry, and concretely provides an application of brphinsted acidic ionic liquid using periodate as an anion as well as a preparation method thereof. The invention provides a method for preparing alpha,omega-dialdehyde. The method comprises the following steps: in a condition of a solution, cycloolefin and/or alkylene oxide and an oxidizing agent are contacted, transparent liquid with white deposition is obtained, transparent liquid and white deposition are obtained by separation, wherein the oxidizing agent is brphinsted acidic ionic liquid using periodate as the anion. The brphinsted acidic ionic liquid using periodate as the anion can be used as an oxidizing agent for carrying out an oxidation reaction is provided for the first time, and the method has the advantages of simple and easily operated process, green and environmental protection, cleaning, and repeated recovery and utilization of the oxidizing agent.

NOVEL PROCESS FOR MAKING OMEGA-AMINOALKYLENIC ALKYL ESTER

-

Paragraph 0184; 0185, (2016/08/17)

A method for making a compound of formula (V): is provided. The method comprises converting a compound of formula (III): to the compound of formula (V), wherein A is a C6-C10 alkene group having at least one carbon-carbon double bond, B is a C6-C10 alkyl chain; and R1 is an alkyl group, and R3 is an oxygenated functional group.

Iron Catalysis for Room-Temperature Aerobic Oxidation of Alcohols to Carboxylic Acids

Jiang, Xingguo,Zhang, Jiasheng,Ma, Shengming

supporting information, p. 8344 - 8347 (2016/07/26)

Oxidation from alcohols to carboxylic acids, a class of essential chemicals in daily life, academic laboratories, and industry, is a fundamental reaction, usually using at least a stoichiometric amount of an expensive and toxic oxidant. Here, an efficient and practical sustainable oxidation technology of alcohols to carboxylic acids using pure O2 or even O2 in air as the oxidant has been developed: utilizing a catalytic amount each of Fe(NO3)3·9H2O/TEMPO/MCl, a series of carboxylic acids were obtained from alcohols (also aldehydes) in high yields at room temperature. A 55 g-scale reaction was demonstrated using air. As a synthetic application, the first total synthesis of a naturally occurring allene, i.e., phlomic acid, was accomplished.

Synthesis, structural characterization and catalysis of ruthenium(II) complexes based on 2,5-bis(2′-pyridyl)pyrrole ligand

Zhong, Yi-Qing,Xiao, Hui-Qiong,Yi, Xiao-Yi

, p. 18113 - 18119 (2016/11/25)

Treatment of the 2,5-bis(2′-pyridyl)pyrrolato (PDP-) anion with {Ru(COD)Cl2}n in THF readily yielded [Ru(PDP)(COD)Cl] (1) in almost quantitative yield. Anion metathesis of 1 in organic solvent by NO3- and OTf- (OTf- = triflato) gave [Ru(PDP)(COD)(NO3)] (2) and [Ru(PDP)(COD)(OTf)] (3), and in aqueous solution by BF4- and PF6- afforded aqueous complexes [Ru(PDP)(COD)(H2O)](BF4) (4+·BF4-) and [Ru(PDP)(COD)(H2O)](PF6) (4+·PF6-), respectively. Treatment of 1 with PhICl2 in CH2Cl2 afforded 5 with halogenated pyrrole. These complexes exhibit similar structure, including one Ru(ii) atom, one 2,5-bis(2′-pyridyl)pyrrole and one monodentate anion or aqua ligand. Each Ru(ii) tightly binds to three adjacent coplanar sites of PDP- ligand to form a meridional configuration. Complex 1 with NaIO4 as the oxidant in EtOAc-CH3CN-H2O (ratio = 3 : 1 : 2) proved to be highly effective in the catalytic oxidation of olefins to carbonyl products.

Aerobic epoxidation catalysed by transition metal substituted polyfluorooxometalates

Bugnola, Marco,Neumann, Ronny

, p. 14534 - 14537 (2016/09/28)

First row transition metal substituted polyfluorooxmetalates with quasi Wells-Dawson structures and a nitro terminal ligand, [NaH2M(NO2)W17F6O55]q-, were used as catalysts for the aerobic epoxidation of cyclic alkenes. The Cu(NO2) analog combined the best traits of conversion and selectivity. Some C-C bond cleavage was also observed and cis isomers reacted preferentially without stereochemical inversion indicating an oxygen atom to double bond concerted reaction.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 638-54-0