636-73-7 Usage
Description
3-Pyridinesulfonic acid is an organic compound with the chemical formula C5H5NO3S. It is a derivative of pyridine, a heterocyclic aromatic compound, and features a sulfonic acid group attached to the third carbon atom. This molecule exhibits acidic properties due to the presence of the sulfonic acid functional group.
Uses
Used in Chemical Synthesis:
3-Pyridinesulfonic acid is used as a precursor in the synthesis of various reaction intermediates, which are essential for the production of a wide range of chemical compounds. Its unique structure and reactivity make it a valuable building block in organic chemistry.
Used in the Synthesis of Silver 3-Pyridinesulfonate:
3-Pyridinesulfonic acid is used as a reactant in the synthesis of silver 3-pyridinesulfonate, a coordination compound that finds applications in various fields, such as catalysis and materials science. The formation of silver 3-pyridinesulfonate involves the reaction of 3-pyridinesulfonic acid with silver ions, resulting in a complex with potential catalytic and sensing properties.
Used in the Synthesis of 3-Pyridinesulfonyl Chloride:
3-Pyridinesulfonic acid is also used in the preparation of 3-pyridinesulfonyl chloride, an important intermediate for the synthesis of various pharmaceuticals, agrochemicals, and other specialty chemicals. The conversion of 3-pyridinesulfonic acid to 3-pyridinesulfonyl chloride typically involves a chlorination reaction, which introduces a reactive chlorine atom to the molecule, facilitating further chemical transformations.
Purification Methods
Purify the acid by recrystallisation from H2O or aqueous EtOH as needles or plates. [pKa: Evans & Brown J Org Chem 27 3127 1962, IR: Arnett & Chawla J Am Chem Soc 100 214 1978.] UV in 50% aqueous EtOH has at 208 and 262nm. The ammonium salt max has m 243o (from H2O), the sulfonyl chloride has m 133-134o (from pet ether), the amide has m 110-111o (from H2O), the hydrochloride has m >300o(dec), and the N-methyl betaine has m 130o (from H2O). [Gastel & Wibaut Recl Trav Chim Pays-Bas 53 1031 1934, McIlvain & Goese J Am Chem Soc 65 2233 1943, Machek Monatsh Chem 72 77 1938, Beilstein 22 I 616, 22 II 309, 22/7 V 552.]
Check Digit Verification of cas no
The CAS Registry Mumber 636-73-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,3 and 6 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 636-73:
(5*6)+(4*3)+(3*6)+(2*7)+(1*3)=77
77 % 10 = 7
So 636-73-7 is a valid CAS Registry Number.
InChI:InChI=1/C5H5NO3S/c7-10(8,9)5-2-1-3-6-4-5/h1-4H,(H,7,8,9)/p-1
636-73-7Relevant articles and documents
Production of pyridine-3-sulfonic acid
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, (2008/06/13)
A method for the production of heavy metal-free pyridine -3-sulfonic acid by oxidation of 3-chloro-pyridine to 3-chloro-pyridine-N-oxide, substitution of the chlorine through a sulfonic acid group, and subsequent reduction to pyridine-3-sulfonic acid. The method can be carried out using raw 3-chloropyridine-N-oxide and direct further reaction of the pyridine-3-sulfonic acid-N-oxide in the presence of Raney nickel in an alkaline solution.
