63444-51-9

Basic information

• Product Name: 6-Methoxy-2-vinylnaphthalene
• Synonyms: 6-METHOXY-2-VINYLNAPHTHALENE;6-Methoxy-2-vinylnaphthalene, 97+%;2-methoxy-6-vinylnaphthalene;6-METHOXY-2-VINYLINSPHTHOLENE;6-Methoxy-2-naphthylethylene;2-ethenyl-6-Methoxynaphthalene
• CAS NO: 63444-51-9
• Molecular Formula: C₁₃H₁₂O
• Molecular Weight: 184.23
• EINECS: 200-110-4
• Product Categories: Heterocyclic Compounds;API;Benzenes
• Mol File: 63444-51-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 88-91 °C
• Boiling Point: 278.19°C (rough estimate)
• Flash Point: 122.7 °C
• Appearance: /
• Density: 1.0120 (rough estimate)
• Vapor Pressure: 0.00091mmHg at 25°C
• Refractive Index: 1.5928 (estimate)
• Storage Temp.: Sealed in dry,Store in freezer, under -20°C
• CAS DataBase Reference: 6-Methoxy-2-vinylnaphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Methoxy-2-vinylnaphthalene(63444-51-9)
• EPA Substance Registry System: 6-Methoxy-2-vinylnaphthalene(63444-51-9)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 63444-51-9(Hazardous Substances Data)

Usage

Chemical Properties

Beige crystalline powder

InChI:InChI=1/C13H12O/c1-3-10-4-5-12-9-13(14-2)7-6-11(12)8-10/h3-9H,1H2,2H3

Upstream product

• 67886-69-5 2-iodo-6-methoxynaphthalene 
• 1826-67-1 vinyl magnesium bromide 
• 4363-34-2 vinylboronic acid 
• 5111-65-9 2-Bromo-6-methoxynaphthalene 
• 1450622-43-1 C₁₄H₁₆O₂ 
• 931-51-1 cyclohexylmagnesiumchloride 
• 32725-05-6 2-<1-hydroxyethyl>-6-methoxynaphthalene 
• 108781-65-3 1-(6-methoxy-2-naphthyl)ethanol 

Downstream Products

• 23981-80-8 naproxen 
• 473999-87-0 (+/-)-2-(6-methoxy-2-naphthyl)-1,2-epoxyethane 
• 377088-74-9 (R)-2-(6-methoxy-2-naphthyl)-1,2-epoxyethane 
• 473999-87-0 (S)-2-(6-methoxy-2-naphthyl)-1,2-epoxyethane 
• 934239-67-5 (E)-2-(4-bromostyryl)-6-methoxynaphthalene 
• 1058162-97-2 phenyl 2-(6 - methoxynaphthalen - 2-yl) propanoate 
• 123871-53-4 2-methoxy-6-(E)-styrylnaphthalene 
• 66719-03-7 2-(6-methoxynaphthalen-2-yl)-N-phenylpropanamide 
• 37414-52-1 2-(6-methoxy-2-naphthyl)-propyl alcohol 

Relevant articles and documents

Oxidations of allylic and benzylic alcohols under inductively-heated flow conditions with gold-doped superparamagnetic nanostructured particles as catalyst and oxygen as oxidant

A continuous flow protocol for the oxidation of allylic and benzylic alcohols to aldehydes and ketones, respectively, using oxygen gas or atmospheric air is reported. The key features of this work are gold nanoparticles that are attached to the surface of nanostructured core shell particles composed of an Fe3O4-containing core and a silica shell. These nanostructured particles exert superparamagnetic properties and thus inductively heat up in an external oscillating electromagnetic field, conditions under which the gold catalyst is able to perform these oxidation reactions.

Fe-promoted cross coupling of homobenzylic methyl ethers with Grignard reagents via sp3 C-O bond cleavage

The first iron-catalyzed formal cross coupling of homobenzylic methyl ethers with alkyl Grignard reagents is realized. The reaction is proposed to proceed through a sequence of dehydroalkoxylation to form the vinyl-intermediate, followed by Fe-catalyzed selective carbometalation to form a benzylic Grignard reagent.

Suzuki cross-coupling reactions between alkenylboronic acids and aryl bromides catalysed by a tetraphosphane-palladium catalyst

A range of alkenylboronic acids undergo Suzuki cross-coupling with aryl bromides in good yields in the presence of [PdCl(C3H 5)]2/cis,cis,cis-1,2,3,4-tetrakis[(diphenylphosphanyl) methyl]cyclopentane as a catalyst. A wide variety of 1-arylprop-1-enes, 2-arylprop-1-enes, 2-arylbut-1-enes and 1,1-diarylethylene or styrene derivatives have been prepared. Moreover, the reaction tolerates several functions, such as acetyl, formyl, nitrile or nitro. Furthermore, this catalyst can be used at low loading, even for reactions of sterically hindered substrates. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.

HYDROFORMYLATION CATALYSED BY RHODIUM COMPLEXES OF TREHALOSE-DERIVED LIGANDS αα and ββ-TREDIP; A HIGHLY REGIOSELECTIVE ROUTE TO α-METHYLARYLPROPIONALDEHYDES

Rhodium complexes of the ligand αα-TREDIP give 62:1 iso-regioselectivity in the hydroformylation of styrene under ambient conditions without excess posphine, higher than any previously reported value.The results are compared with those obtained with other ligands, and extended to preparation of 2-(6-methoxy-2-naphthyl)-propanal, a precursor of the anti-inflammatory drug naproxen.