6338-55-2 Usage
Description
2-[2-(2-AMINOETHOXY)ETHOXY]ETHANOL, also known as (PEO)3-monoamine, is a poly(ethylene oxide) (PEO) blocking agent that is utilized to prevent nonspecific adsorption of analytes in various applications, particularly in covalent protein coupling techniques such as ELISA. 2-[2-(2-AMINOETHOXY)ETHOXY]ETHANOL is characterized by its ability to reduce the adsorption of IgG when coated on carboxylic-terminated surfaces, thereby enhancing the specificity and accuracy of the assays.
Uses
Used in Diagnostic Applications:
2-[2-(2-AMINOETHOXY)ETHOXY]ETHANOL is used as a blocking agent for preventing nonspecific adsorption of analytes in diagnostic assays such as ELISA. The application reason is to enhance the specificity and accuracy of the assays by reducing the adsorption of IgG on carboxylic-terminated surfaces.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-[2-(2-AMINOETHOXY)ETHOXY]ETHANOL is used as a stabilizing agent for protein formulations. The application reason is to improve the stability and shelf life of protein-based drugs by minimizing their interaction with surfaces and reducing the risk of aggregation.
Used in Research and Development:
2-[2-(2-AMINOETHOXY)ETHOXY]ETHANOL is used as a research tool for studying protein-surface interactions and developing novel protein coupling techniques. The application reason is to provide a means to investigate the underlying mechanisms of nonspecific adsorption and to design more effective strategies for minimizing it in various experimental setups.
Used in Surface Modification:
In the field of surface modification, 2-[2-(2-AMINOETHOXY)ETHOXY]ETHANOL is used as a coating agent to create surfaces with reduced protein adsorption properties. The application reason is to develop surfaces that are less prone to fouling and biocompatibility issues, which can be beneficial in various applications such as medical devices, sensors, and lab-on-a-chip systems.
Check Digit Verification of cas no
The CAS Registry Mumber 6338-55-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,3,3 and 8 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 6338-55:
(6*6)+(5*3)+(4*3)+(3*8)+(2*5)+(1*5)=102
102 % 10 = 2
So 6338-55-2 is a valid CAS Registry Number.
InChI:InChI=1/C6H15NO3/c7-1-3-9-5-6-10-4-2-8/h8H,1-7H2
6338-55-2Relevant articles and documents
Cofactor-free detection of phosphatidylserine with cyclic peptides mimicking lactadherin
Zheng, Hong,Wang, Fang,Wang, Qin,Gao, Jianmin
, p. 15280 - 15283 (2011)
Cyclic peptides (cLacs) are designed to mimic the natural phosphatidylserine (PS) binding protein lactadherin. Unlike annexin V or its small molecule mimics, the cLac peptides selectively target PS-presenting membranes with no need for metal cofactors. We further show that a fluorophore-labeled cLac effectively stains early apoptotic cells. The small size and facile conjugation with a variety of imaging tracers make the cLac design promising for imaging cell death in vitro as well as in living organisms.
MERTK DEGRADERS AND USES THEREOF
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Paragraph 00974, (2020/01/31)
The present invention provides compounds, compositions thereof, and methods of using the same.
The effect of monosaccharides on self-assembly of benzenetricarboxamides
Wang, Jue,Qi, Wenjing,Chen, Guosong
supporting information, p. 587 - 591 (2019/01/04)
The interaction between monosaccharides exhibits an important role in the assembly of monosaccharide-containing molecules. In this work, three common monosaccharides, glucose, galactose and mannose, are employed to investigate the effect of monosaccharide on the self-assembly of benzenetricarboxamide (BTA) core-containing molecules. In the presence of monosaccharides, three benzenetricarboxamide derivatives aggregate into different ordered structures. When alanine linkers are introduced to these molecules between the core and the monosacchride, morphologies of three types of monosaccharide BTAs turned to disordered, meanwhile their structures become similar with the increase of the length of alanine linkers, indicating the disappearance of the monosaccharide effects.
