6320-40-7

Basic information

• Product Name: 2,4,6-TRIBROMOTOLUENE
• Synonyms: 2,4,6-TRIBROMOTOLUENE;Benzene, 1,3,5-tribromo-2-methyl-;2,4,6-Tribromotoluene 98%;2,4,6-Tribromotoluene, 98+%;1,3,5-Tribromo-2-methylbenzene;2,4,6-Tribromotoluene,97%;Einecs 228-672-2;2-Methyl-1,3,5-tribromobenzene
• CAS NO: 6320-40-7
• Molecular Formula: C₇H₅Br₃
• Molecular Weight: 328.83
• EINECS: 228-672-2
• Product Categories: Aromatic Hydrocarbons (substituted) & Derivatives
• Mol File: 6320-40-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 68-71 °C(lit.)
• Boiling Point: 290°C
• Flash Point: 290°C
• Appearance: Yellow to light brown/Powder and/or Chunks
• Density: 2,479 g/cm3
• Vapor Pressure: 0.00356mmHg at 25°C
• Refractive Index: 1.6340 (estimate)
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: Chloroform (Sparingly), Methanol (Slightly)
• Water Solubility: Insoluble in water.
• BRN: 2359313
• CAS DataBase Reference: 2,4,6-TRIBROMOTOLUENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6-TRIBROMOTOLUENE(6320-40-7)
• EPA Substance Registry System: 2,4,6-TRIBROMOTOLUENE(6320-40-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-24/25
• WGK Germany: 3
• Hazardous Substances Data: 6320-40-7(Hazardous Substances Data)

Usage

Chemical Properties

Yellow powder

Uses

2,4,6-Tribromotoluene acts as a reagent in the synthesis of non-proteinogenic α-amino acids.

InChI:InChI=1/C7H5Br3/c1-4-6(9)2-5(8)3-7(4)10/h2-3H,1H3

Upstream product

• 13194-73-5 3,5-dibromo-4-methylaniline 
• 22230-45-1 2,3,5,6-tetrabromo-4-nitrotoluene 
• 108-88-3 toluene 
• 857007-53-5 2,4,6-tribromo-3-methyl-5-nitro-aniline 
• 873971-72-3 2,3,4,6-tetrabromo-5-nitro-toluene 
• 679834-22-1 1,2,4,5-tetrabromo-3-isopropyl-6-methyl-benzene 
• 39664-46-5 2,3,4,6-tetrabromotoluene 
• 108-44-1 1-amino-3-methylbenzene 
• 56-23-5 tetrachloromethane 
• 31543-75-6 2,4-dibromotoluene 
• 7726-95-6 bromine 
• 71642-16-5 3-methyl-2,4,6-tribromoaniline 

Downstream Products

• 2537-67-9 2,4,6-tribromoacetophenone 
• 873415-10-2 1-(2,4,6-tribromo-phenyl)-ethanol 
• 1774401-31-8 2,4,6-tris(4-carboxyphenyl)toluene 
• 1335150-57-6 C₁₆H₁₄Br₂O₃ 
• 74151-36-3 2-(2,4,6-Tribromostyryl)-4-(δ-diethylamino-α-methylbutylamino)-6-nitroquinazoline 
• 74151-35-2 N⁴-{7-Chloro-2-[(E)-2-(2,4,6-tribromo-phenyl)-vinyl]-quinazolin-4-yl}-N¹,N¹-diethyl-pentane-1,4-diamine 
• 105997-27-1 N¹,N¹-Diethyl-N⁴-{2-[(E)-2-(2,4,6-tribromo-phenyl)-vinyl]-quinazolin-4-yl}-pentane-1,4-diamine 
• 246247-20-1 2,4,6-tris(4-ethynylbenzonitrile)toluene 
• 246247-41-6 2,4,6-tris(trimethylsilylethynyl)toluene 
• 28744-45-8 2,4,6-Trichlorobenzylidene dichloride 
• 66788-13-4 2,6-dibromo-1,4-dimethylbenzene 
• 51209-82-6 3,5-dibromo-1,2-dimethyl-benzene 
• 29785-82-8 α,α-Dichlor-2,4,6-tribromtoluol 
• 51990-65-9 α,α,2,4,6-Pentabromtoluol 

Relevant articles and documents

SYNTHESIS OF AROMATIC POLYHALOGENATED HALOMETHYL COMPOUNDS

The present invention discloses a process for the preparation of highly pure Pentabromobenzyl bromide, PBB-Br, wherein the benzylic bromination reaction is carried out in a suitable organic solvent in the presence of water and wherein the reaction temperature is such that it is sufficient to activate the initiator but not high enough to consume a substantial amount thereof.

Efficient Catalysis of Hydrodediazoniations in Dimethylformamide

For hydrodediazoniations (the replacement of a diazo group by hydrogen) in DMF, several substances act as catalysts through their ability to serve as electron donors and initiate free-radical reactions.A general procedure has been developed in which FeSO4 speeds the conversion and leads to higher yields.Trapping experiments demonstrated the presence of free-radical intermediates.N,N-Dimethylacetamide was found to rival DMF as a source of hydrogen atoms.

Deuteriodediazoniation: A general method for the replacement of a diazonium group by deuterium

Aromatic amino groups are replaced with deuterium via a diazonium salt intermediate. Dimethylformamide-d7 is the deuterium donor in this mild replacement method that yields aromatic-d1 products in high isotopic purity. The presence of methyl groups lowers the isotopic purity of the products.