6306-46-3 Usage
Description
4,4'-(BromoMethylene)bis(chlorobenzene), with the molecular formula C13H8Br2Cl2, is a white solid chemical compound that has a molecular weight of 361.92 g/mol. It is primarily recognized for its role as an intermediate in the synthesis of various products, including pharmaceuticals, agrochemicals, and dyes.
Uses
Used in Pharmaceutical Industry:
4,4'-(BromoMethylene)bis(chlorobenzene) is used as a chemical intermediate for the synthesis of pharmaceuticals, contributing to the development of new drugs and medicines.
Used in Agrochemical Industry:
In the agrochemical sector, 4,4'-(BromoMethylene)bis(chlorobenzene) serves as an intermediate, playing a crucial role in the production of agrochemicals that are vital for agricultural applications.
Used in Dye Industry:
4,4'-(BroMoMethylene)bis(chlorobenzene) is also utilized as an intermediate in the synthesis of dyes, which are essential for coloring fabrics, plastics, and other materials.
Used in Organic Electronic Materials:
4,4'-(BromoMethylene)bis(chlorobenzene) finds application in the production of organic electronic materials, which are increasingly important in the development of advanced electronic devices and technologies.
Used as a Reagent in Organic Synthesis:
Furthermore, it is employed as a reagent in organic synthesis, facilitating various chemical reactions and processes in the laboratory and industrial settings.
However, it is important to note that 4,4'-(BromoMethylene)bis(chlorobenzene) is considered a potential environmental contaminant and has been identified as a persistent organic pollutant. Therefore, it may pose health risks if not handled or disposed of properly. It is crucial to exercise caution and adhere to proper safety procedures when working with this chemical compound.
Check Digit Verification of cas no
The CAS Registry Mumber 6306-46-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,3,0 and 6 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 6306-46:
(6*6)+(5*3)+(4*0)+(3*6)+(2*4)+(1*6)=83
83 % 10 = 3
So 6306-46-3 is a valid CAS Registry Number.
6306-46-3Relevant articles and documents
SUBSTITUTED NAPHTHYRIDINONE COMPOUNDS USEFUL AS T CELL ACTIVATORS
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Page/Page column 169, (2020/01/24)
Disclosed are compounds of Formula (I) or a salt thereof, wherein: R1, R2, R3, R4, R5, and m are defined herein. Also disclosed are methods of using such compounds to inhibit the activity of one or both of diacylglycerol kinase alpha (DGKα) and diacylglycerol kinase zeta (DGKζ), and pharmaceutical compositions comprising such compounds. These compounds are useful in the treatment of viral infections and proliferative disorders, such as cancer.
General and Mild Nickel-Catalyzed Cyanation of Aryl/Heteroaryl Chlorides with Zn(CN)2: Key Roles of DMAP
Zhang, Xingjie,Xia, Aiyou,Chen, Haoyi,Liu, Yuanhong
supporting information, p. 2118 - 2121 (2017/04/27)
A new and general nickel-catalyzed cyanation of hetero(aryl) chlorides using less toxic Zn(CN)2 as the cyanide source has been developed. The reaction relies on the use of inexpensive NiCl2·6H2O/dppf/Zn as the catalytic system and DMAP as the additive, allowing the cyanation to occur under mild reaction conditions (50-80 °C) with wide functional group tolerance. DMAP was found to be crucial for successful transformation, and the reaction likely proceeds via a Ni(0)/Ni(II) catalysis based on mechanistic studies. The method was also successfully extended to aryl bromides and aryl iodides.
N-heterocyclic carbene-catalyzed cross-coupling of aromatic aldehydes with activated alkyl halides
Padmanaban, Mohan,Biju, Akkattu T.,Glorius, Frank
, p. 98 - 101 (2011/03/19)
N-Heterocyclic carbene-catalyzed umpolung of aldehydes followed by their interception with diarylbromomethanes has been reported. This conceptually novel transition-metal-free cross-coupling of aldehydes with alkyl halides works well at low catalyst loadings and under mild reaction conditions leading to the formation of diaryl acetophenone derivatives in good yields. In addition, α-halo ketones and esters can also be used as aldehyde reaction partners.
