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63059-29-0

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63059-29-0 Usage

Description

2-IODOBENZENE-1-SULFONYL CHLORIDE, also known as 2-Iodobenzenesulfonyl chloride, is an organic compound with the chemical formula C6H4I(SO2Cl). It is a derivative of benzene with an iodine atom at the 2nd position, a sulfonyl group at the 1st position, and a chlorine atom attached to the sulfonyl group. 2-IODOBENZENE-1-SULFONYL CHLORIDE is known for its reactivity and is commonly used in the synthesis of various pharmaceuticals and chemical compounds.

Uses

Used in Pharmaceutical Industry:
2-IODOBENZENE-1-SULFONYL CHLORIDE is used as a chemical intermediate for the synthesis of various pharmaceutical compounds. Its reactivity allows it to be a key component in the development of new drugs and therapies.
Used in Cancer Therapy:
2-IODOBENZENE-1-SULFONYL CHLORIDE is used as phosphoglycerate mutase 1 inhibitors, which are considered a promising target for cancer therapy. By inhibiting this enzyme, it may help in the development of new treatments for various types of cancer.

Check Digit Verification of cas no

The CAS Registry Mumber 63059-29-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,0,5 and 9 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 63059-29:
(7*6)+(6*3)+(5*0)+(4*5)+(3*9)+(2*2)+(1*9)=120
120 % 10 = 0
So 63059-29-0 is a valid CAS Registry Number.
InChI:InChI=1/C6H4ClIO2S/c7-11(9,10)6-4-2-1-3-5(6)8/h1-4H

63059-29-0 Well-known Company Product Price

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  • TCI America

  • (I0811)  2-Iodobenzenesulfonyl Chloride  >98.0%(GC)(T)

  • 63059-29-0

  • 1g

  • 1,250.00CNY

  • Detail
  • TCI America

  • (I0811)  2-Iodobenzenesulfonyl Chloride  >98.0%(GC)(T)

  • 63059-29-0

  • 5g

  • 3,890.00CNY

  • Detail

63059-29-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Iodobenzene-1-Sulfonyl Chloride

1.2 Other means of identification

Product number -
Other names 2-Iodobenzenesulfonyl chloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:63059-29-0 SDS

63059-29-0Relevant articles and documents

Functionalization of α-C(sp3)?H Bonds in Amides Using Radical Translocating Arylating Groups

Radhoff, Niklas,Studer, Armido

, p. 3561 - 3565 (2021/01/04)

α-C?H arylation of N-alkylamides using 2-iodoarylsulfonyl radical translocating arylating (RTA) groups is reported. The method allows the construction of α-quaternary carbon centers in amides. Various mono- and disubstituted RTA-groups are applied to the arylation of primary, secondary, and tertiary α-C(sp3)?H-bonds. These radical transformations proceed in good to excellent yields and the cascades comprise a 1,6-hydrogen atom transfer, followed by a 1,4-aryl migration with subsequent SO2 extrusion.

One-pot, Pd/Cu-catalysed synthesis of alkynyl-substituted 3-ylidene-dihydrobenzo[d]isothiazole 1,1-dioxides

Etsè, Koffi Sénam,Dassonneville, Benjamin,Zaragoza, Guillermo,Demonceau, Albert

, p. 789 - 793 (2017/03/31)

Enyne-substituted benzoisothiazole derivatives have been synthesised under one-pot, operationally simple conditions using 2-iodo-N-(trimethylsilylethynyl)benzenesulfonamides and terminal alkynes as starting materials and a palladium–copper-based catalytic system. The structure of these heterocycles has been demonstrated by NMR spectroscopy and confirmed by X-ray crystallographic analysis. A plausible reaction mechanism has been proposed.

Abstraction of iodine from aromatic iodides by alkyl radicals: Steric and electronic effects

Dolenc, Darko,Plesnicar, Bozo

, p. 8028 - 8036 (2007/10/03)

Abstraction of the iodine atom from aryl iodides by alkyl radicals takes place in some cases very efficiently despite the unfavorable difference in bond dissociation energies of C-I bonds in alkyl and aryl iodides. The abstraction is most efficient in iod

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