6283-13-2

Basic information

• Product Name: N-(2-phenylethyl)butanamide
• Synonyms: butanamide, N-(2-phenylethyl)-; N-(2-Phenylethyl)butanamide
• CAS NO: 6283-13-2
• Molecular Formula: C₁₂H₁₇NO
• Molecular Weight: 191.2695
• Mol File: 6283-13-2.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 368.8°C at 760 mmHg
• Flash Point: 220.6°C
• Density: 0.984g/cm³
• Vapor Pressure: 1.24E-05mmHg at 25°C
• Refractive Index: 1.508
• CAS DataBase Reference: N-(2-phenylethyl)butanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-phenylethyl)butanamide(6283-13-2)
• EPA Substance Registry System: N-(2-phenylethyl)butanamide(6283-13-2)

Safety Data

• Hazardous Substances Data: 6283-13-2(Hazardous Substances Data)

Upstream product

• 64-04-0 phenethylamine 
• 141-75-3 butyryl chloride 
• 107-92-6 butyric acid 
• 110-69-0 butyraldehyde oxime 
• 123-73-9 crotonaldehyde 
• 623-42-7 butanoic acid methyl ester 
• 109-21-7 butyl butyrate 
• 71-36-3 butan-1-ol 
• 105-54-4 butanoic acid ethyl ester 
• 123-20-6 vinyl n-butyrate 
• 57392-44-6 2,2,2-trichloroethyl butyrate 

Downstream Products

• 23068-45-3 N-Butyl-2-phenylethylamine 
• 7661-37-2 1-propylisoquinoline 

Relevant articles and documents

Volatiles from the Psychrotolerant Bacterium Chryseobacterium polytrichastri

The flavobacterium Chryseobacterium polytrichastri was investigated for its volatile profile by use of a closed-loop stripping apparatus (CLSA) and subsequent GC-MS analysis. The analyses revealed a rich headspace extract with 71 identified compounds. Compound identification was based on a comparison to library mass spectra for known compounds and on a synthesis of authentic standards for unknowns. Important classes were phenylethyl amides and a series of corresponding imines and pyrroles.

Facile direct synthesis of amides from trichloroethyl esters using catalytic DBU

A practical method for the direct synthesis of amide compounds is described. Using small quantities of DBU as a catalyst, the direct conversion of 2,2,2-trichloroethyl esters to their corresponding amides was readily achieved. Based on this protocol, various amide compounds were successfully synthesized in high yield, suggesting a promising approach for the practical one-pot aminolysis from 2,2,2-trichloroethyl protected esters.

Direct Synthesis of Amides by Dehydrogenative Coupling of Amines with either Alcohols or Esters: Manganese Pincer Complex as Catalyst

The first example of base-metal-catalysed synthesis of amides from the coupling of primary amines with either alcohols or esters is reported. The reactions are catalysed by a new manganese pincer complex and generate hydrogen gas as the sole byproduct, thus making the overall process atom-economical and sustainable.