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  • 6280-80-4 Structure
  • Basic information

    1. Product Name: 2-Formylphenoxyacetic acid
    2. Synonyms: TIMTEC-BB SBB008189;O-FORMYLPHENOXYACETIC ACID;(2-formylphenoxy)-aceticaci;2-(2-Formylphenoxy)acetic acid;2-Carboxymethoxybenzaldehyde;Acetic acid, (2-formylphenoxy)-;Acetic acid, (o-formylphenoxy)-;AKOS B005809
    3. CAS NO:6280-80-4
    4. Molecular Formula: C9H8O4
    5. Molecular Weight: 180.16
    6. EINECS: 228-480-9
    7. Product Categories: Phenoxyacetic Acids and Alcohols (substituted);Aldehydes;C9;Carbonyl Compounds;Building Blocks;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks
    8. Mol File: 6280-80-4.mol
    9. Article Data: 16
  • Chemical Properties

    1. Melting Point: 129.5-132 °C(lit.)
    2. Boiling Point: 272.96°C (rough estimate)
    3. Flash Point: 151.1 °C
    4. Appearance: light brown crystalline powder
    5. Density: 1.2933 (rough estimate)
    6. Vapor Pressure: 6.14E-06mmHg at 25°C
    7. Refractive Index: 1.4500 (estimate)
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. PKA: 3.04±0.10(Predicted)
    11. Sensitive: Air Sensitive
    12. BRN: 2096797
    13. CAS DataBase Reference: 2-Formylphenoxyacetic acid(CAS DataBase Reference)
    14. NIST Chemistry Reference: 2-Formylphenoxyacetic acid(6280-80-4)
    15. EPA Substance Registry System: 2-Formylphenoxyacetic acid(6280-80-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: 36/37/38
    3. Safety Statements: 24/25
    4. WGK Germany: 3
    5. RTECS:
    6. TSCA: Yes
    7. HazardClass: N/A
    8. PackingGroup: N/A
    9. Hazardous Substances Data: 6280-80-4(Hazardous Substances Data)

6280-80-4 Usage

Description

2-Formylphenoxyacetic acid is a light brown crystalline powder that serves as a key intermediate in the synthesis of various organic compounds, particularly in the pharmaceutical and chemical industries. Its unique chemical structure allows for the formation of a wide range of derivatives, making it a versatile building block for the development of new molecules with potential applications in different fields.

Uses

Used in Pharmaceutical Industry:
2-Formylphenoxyacetic acid is used as a synthetic intermediate for the development of azomethine derivatives, which are known for their diverse biological activities, including potential applications in the treatment of various diseases and disorders. The synthesis of these derivatives is crucial for expanding the range of available pharmaceuticals and improving patient outcomes.
Used in Chemical Industry:
In the chemical industry, 2-Formylphenoxyacetic acid is utilized in the preparation of specific ligands, such as L(1)H(2) and L(2)H(2). These ligands are essential components in various chemical processes and reactions, often playing a critical role in enhancing the efficiency and selectivity of these processes. The use of 2-Formylphenoxyacetic acid in ligand synthesis contributes to the advancement of chemical research and the development of new materials and products.
Overall, 2-Formylphenoxyacetic acid is a valuable compound with applications in both the pharmaceutical and chemical industries, showcasing its importance in the synthesis of various organic compounds and the development of new products and therapies.

Check Digit Verification of cas no

The CAS Registry Mumber 6280-80-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,2,8 and 0 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 6280-80:
(6*6)+(5*2)+(4*8)+(3*0)+(2*8)+(1*0)=94
94 % 10 = 4
So 6280-80-4 is a valid CAS Registry Number.
InChI:InChI=1/C9H8O4/c10-5-7-3-1-2-4-8(7)13-6-9(11)12/h1-5H,6H2,(H,11,12)/p-1

6280-80-4 Well-known Company Product Price

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  • Alfa Aesar

  • (A14605)  2-Formylphenoxyacetic acid, 98%   

  • 6280-80-4

  • 25g

  • 240.0CNY

  • Detail
  • Alfa Aesar

  • (A14605)  2-Formylphenoxyacetic acid, 98%   

  • 6280-80-4

  • 100g

  • 675.0CNY

  • Detail

6280-80-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Formylphenoxyacetic acid

1.2 Other means of identification

Product number -
Other names 2-(2-formylphenoxy)acetic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6280-80-4 SDS

6280-80-4Relevant articles and documents

One-dimensional Europium-coordination polymer as luminescent sensor for highly selective and sensitive detection of 2,4,6-trinitrophenol

Gao, Hongyan,Li, Dongping,Li, Yongxiu,Liu, Yanzhu,Sun, Qingyan,Zhou, Hongbo

, (2022)

Three isostructural lanthanide coordination polymers (LnCPs), [Ln(L)6(DMF)]n {HL = 2-(2-formylphenoxy) acetic acid, Ln = Sm (1); Eu (2); Tb (3)} have been synthesized by solvothermal reaction and characterized. Single crystal analyse

Organocatalytic Synthesis of Fused Bicyclic 2,3-Dihydro-1,3,4-oxadiazoles through an Intramolecular Cascade Cyclization

Fugard, Alison J.,Thompson, Bethany K.,Slawin, Alexandra M. Z.,Taylor, James E.,Smith, Andrew D.

supporting information, p. 5824 - 5827 (2015/12/11)

Hydrazone-carboxylic acids undergo intramolecular cyclization in the presence of pivaloyl chloride, iPr2NEt, and catalytic DABCO to form a range of substituted fused tricyclic 2,3-dihydro-1,3,4-oxadiazoles in high yields.

A new fluorescent pH probe for imaging lysosomes in living cells

Lv, Hong-Shui,Huang, Shu-Ya,Xu, Yu,Dai, Xi,Miao, Jun-Ying,Zhao, Bao-Xiang

supporting information, p. 535 - 538 (2014/01/23)

A new rhodamine B-based pH fluorescent probe has been synthesized and characterized. The probe responds to acidic pH with short response time, high selectivity and sensitivity, and exhibits a more than 20-fold increase in fluorescence intensity within the pH range of 7.5-4.1 with the pKa value of 5.72, which is valuable to study acidic organelles in living cells. Also, it has been successfully applied to HeLa cells, for its low cytotoxicity, brilliant photostability, good membrane permeability and no 'alkalizing effect' on lysosomes. The results demonstrate that this probe is a lysosome-specific probe, which can selectively stain lysosomes and monitor lysosomal pH changes in living cells.

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