628-50-2 Usage
Description
3-Methylbutyl Chloroformate is a colorless to pale yellow liquid with a pungent odor, characterized by its use in the synthesis of pharmaceuticals and agrochemicals. It serves as a reagent in organic synthesis, particularly for the formation of esters and other organic compounds. Due to its reactivity with water and strong oxidizing agents, it is considered a skin and eye irritant, necessitating careful handling and storage in well-ventilated areas with appropriate safety measures.
Uses
Used in Pharmaceutical Synthesis:
3-Methylbutyl Chloroformate is used as a key intermediate in the synthesis of various pharmaceutical compounds, contributing to the development of new drugs and therapeutic agents.
Used in Agrochemical Production:
In the agrochemical industry, 3-Methylbutyl Chloroformate is utilized as a precursor in the production of pesticides and other crop protection agents, enhancing agricultural productivity and crop protection.
Used as a Reagent in Organic Synthesis:
3-Methylbutyl Chloroformate is employed as a reagent in organic synthesis processes, particularly for the formation of esters and other organic compounds, facilitating the creation of a wide range of chemical products.
Used in Research and Development:
3-Methylbutyl Chloroformate is utilized in research and development settings for exploring new chemical reactions and synthesizing novel compounds, contributing to advancements in the field of chemistry and related disciplines.
Check Digit Verification of cas no
The CAS Registry Mumber 628-50-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,2 and 8 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 628-50:
(5*6)+(4*2)+(3*8)+(2*5)+(1*0)=72
72 % 10 = 2
So 628-50-2 is a valid CAS Registry Number.
628-50-2Relevant articles and documents
Prodrugs of NH-acidic compounds
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Page/Page column 415, (2015/11/16)
The invention provides a method of sustained delivery of a lactam, imide, amide, sulfonamide, carbamate or urea containing parent drug by administering to a patient an effective amount of a prodrug compound of the invention wherein upon administration to the patient, release of the parent drug from the prodrug is sustained release. Prodrug compounds suitable for use in the methods of the invention are labile conjugates of parent drugs that are derivatized through carbonyl linked prodrug moieties. The prodrug compounds of the invention can be used to treat any condition for which the lactam, imide, amide, sulfonamide, carbamate or urea containing parent drug is useful as a treatment.
Preparation of chloroformates using bis(trichloromethyl)carbonate
Shi, Haibo,Hu, Weixiao,Sun, Yaquan
, p. 708 - 709 (2007/10/03)
The synthesis of eight chloroformates using bis(trichloromethyl) carbonate(BTC) is reported. It has been found that the yields by this BTC method are improved over the earlier phosgene method, and sodium hydroxide is better than pyridine as catalyst for the preparation of phenyl chloroformate.
