626-39-1 Usage
Description
Tribromobenzene, also known as 1,3,5-tribromobenzene (TBB), is an organic compound with the chemical formula C6H3Br3. It is a brominated derivative of benzene, featuring three bromine atoms attached to the benzene ring. Tribromobenzene exists as a lump powder and is known for its chemical properties and various applications across different industries.
Uses
1. Used in Drug Manufacturing:
Tribromobenzene is utilized as an intermediate in the drug manufacturing process. Its unique chemical structure allows it to be a valuable component in the synthesis of various pharmaceutical compounds.
2. Used in Organic Synthesis:
As a substituted bromobenzene, tribromobenzene serves as a general reagent in organic synthesis. Its bromine atoms can be replaced with other functional groups, making it a versatile building block for creating a wide range of organic molecules.
3. Used as an Internal Standard in Analysis:
Tribromobenzene is employed as an internal standard during the derivatization step in the determination of cyanide in human plasma and urine by gas chromatography-mass spectrometry. This application ensures accurate and reliable measurements by accounting for any variations in the analytical process.
4. Used in the Preparation of Inhibitors:
Tribromobenzene is a reagent that can be used in the preparation of different inhibitors. Its chemical properties make it suitable for the development of compounds that can inhibit specific biological or chemical processes.
5. Used in Palladium-Catalyzed Reactions:
Tribromobenzene is a general reagent in palladium-catalyzed reactions, which are widely used in organic chemistry for the formation of carbon-carbon and carbon-heteroatom bonds. Its presence can enhance the efficiency and selectivity of these reactions.
6. Used in the Synthesis of Grignard Reagents:
Tribromobenzene is also used in the synthesis of Grignard reagents, which are important in organic chemistry for their ability to add to carbonyl groups and participate in various carbon-carbon bond-forming reactions.
7. Used in the Formation of Molecular Complexes:
Tribromobenzene forms molecular complexes of 1:2 stoichiometry with [60]and [70] fullerenes. These complexes have potential applications in materials science and nanotechnology.
8. Used in the Synthesis of Novel Monomers:
Tribromobenzene reacts with perfluoroalkenylzinc reagent in the presence of Pd(Ph3)4 catalyst to yield a novel trifunctional monomer, 1,3,5-tris(α, β, β-trifluorovinyl)benzene. This monomer can be used in the development of new polymers and materials with unique properties.
Environmental fate
Photolytic. Peijnenburg et al. (1992) investigated the photodegradation of a variety of
substituted aromatic halides using a Rayonet RPR-208 photoreactor equipped with 8 RUL 3,000-
? lamps (250–350 nm). The reaction of 1,3,5-tribromobenzene (initial concentration 10-5 M) was
conducted in distilled water and maintained at 20 °C. Though no products were identified, the
investigators reported photohydrolysis was the dominant transformation process. The measured
pseudo-first-order reaction rate constant and corresponding half-life were 0.005/min and 140.5
min., respectively.
Chemical/Physical. 1,3,5-Tribromobenzene will not hydrolyze to any reasonable extent.
Purification Methods
Crystallise it from glacial acetic acid/water (4:1), then wash with chilled EtOH and dry in air. [Beilstein 5 H 213, 5 IV 685.]
Check Digit Verification of cas no
The CAS Registry Mumber 626-39-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,2 and 6 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 626-39:
(5*6)+(4*2)+(3*6)+(2*3)+(1*9)=71
71 % 10 = 1
So 626-39-1 is a valid CAS Registry Number.
InChI:InChI=1/C6H3Br3/c7-4-1-5(8)3-6(9)2-4/h1-3H
626-39-1Relevant articles and documents
Biddle et al.
, p. 311 (1968)
Synthesis method of high-purity phloroglucinol compound
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, (2021/06/09)
The invention discloses a one-step chemical catalytic synthesis method of high-purity phloroglucinol by taking 3,5-dichlorophenol as a starting material and taking strong base and a catalyst as auxiliary materials. Through the method, the phloroglucinol compound with high molar yield, high purity and low cost can be effectively synthesized.
PROCESS FOR THE PREPARATION OF ORGANIC BROMIDES
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Paragraph 00139; 00141, (2017/07/28)
The present invention provides a process for the preparation of organic bromides, by a radical bromodecarboxylation of carboxylic acids with a bromoisocyanurate.
COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME
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, (2015/10/28)
This invention relates to a compound for an organic electroluminescent device and to an organic electroluminescent device including the same. This compound for an organic electroluminescent device including the same is improved in thermal stability and light emission efficiency. When this compound is used as a hole transport layer material, a triplet energy of a phosphorescent light emitting material is increased, thus improving the efficiency of the organic electroluminescent device.