625-45-6Relevant articles and documents
Ruthenium Catalyzed Dehydrogenation of Alcohols and Mechanistic Study
Awasthi, Mahendra K.,Singh, Sanjay K.
supporting information, p. 14912 - 14923 (2019/11/03)
We synthesized pyridylamine ligated arene-Ru(II) complexes and employed these complexes for the catalytic acceptorless dehydrogenation of primary alcohols to carboxylic acids. All the synthesized complexes [Ru]-1-[Ru]-10 are characterized using several spectro-analytical techniques, and the structures of complexes [Ru]-1, [Ru]-2, and [Ru]-5 are determined using single crystal X-ray crystallography. Efficient catalytic conversion of primary alcohols to potassium carboxylates or carboxylic acids is achieved in toluene with the quantitative release of hydrogen gas. The studied protocol for carboxylic acid synthesis with hydrogen generation is also employed for a wide range of substrates, including aliphatic alcohols, aromatic alcohols, and heteroaromatic alcohols, to obtain respective carboxylic acids in good yields (up to 86%). The studied arene-Ru catalysts also exhibit superior catalytic activity for the bulk reaction to achieve a turnover number of 1378. Moreover, extensive mass investigations are also performed to elucidate the mechanistic pathway by identifying the crucial catalytic intermediates, including aldehyde and diol coordinated Ru species under the catalytic and controlled reaction conditions.
Synthesis, molecular modeling, and DNA binding of new schiff base ruthenium(II) complex and its catalytic oxidation
El-Shobaky, Amira R.
, p. 1481 - 1488 (2015/06/08)
A new ruthenium(II) complex was derived from 4-aminoantipyrine Schiff base (L). The structural feature has been confirmed through elemental, magnetic susceptibility, and molar conductivity analysis. IR, UV-Vis, and 1H NMR spectral studies show that the complex has composition of [Ru LCl2] type, suggesting an octahedral geometry around the central metal ion. DNA interaction studies throw spectroscopic and viscosity measurement confirmed that complex bind through intercalative mode, which confirmed by computational data throw the calculation of thermodynamic parameter. Also, catalytic oxidation of the Ru(II) complex was carried out showing that the complex is efficient catalyst for the oxidation.
Larvicidal activity and click synthesis of 2-alkoxyl-2-(1,2,3-triazole-1- yl)acetamide library
Su, Na-Na,Xiong, Li-Xia,Yu, Shu-Jing,Zhang, Xiao,Cui, Can,Li, Zheng-Ming,Zhao, Wei-Guang
, p. 484 - 493 (2013/07/28)
Heterogeneous copper-in-charcoal-catalyzed click synthesis in 96-well polypropylene filter plates is an efficient method for the rapid generation of sufficient pure 2-alkoxyl-2-(1,2,3-triazole-1-yl) acetamide derivatives library by simple filtration, which directly assay the products for larvicidal activity against mosquitoes. In this procedure, copper nanoparticles on charcoal were arrayed into each well on a 96-well plate, reagents were delivered using a pipette gun, and a constant temperature shaker bath was used to complete the click reaction in 24-72 hours under temperature-controlled conditions. The results of bioassays indicated that the target compounds possessed excellent larvacidal activities against mosquitoes. In particular, the larvacidal activities against mosquitoes of compounds 8[2,3] and 8[7,1] at 2g.mL-1 were 100% and 73%, respectively.
