621-31-8 Usage
Description
3-Ethylaminophenol, also known as N-ethylaniline, is an organic compound with the chemical formula C8H11NO. It is a very viscous deep orange liquid at room temperature. 3-ETHYLAMINOPHENOL is characterized by its aromatic ring structure with an ethylamine group attached to the third carbon position, which gives it unique chemical properties and potential applications in various industries.
Uses
Used in Hair Dye Industry:
3-Ethylaminophenol is used as an intermediate chemical for the production of hair dye compositions. Its ability to form color complexes with hair proteins makes it a valuable component in the formulation of hair dyes, providing a wide range of shades and hues.
Used in Chemical Synthesis:
3-Ethylaminophenol can also be used as a building block in the synthesis of various organic compounds, such as dyes, pharmaceuticals, and other specialty chemicals. Its reactivity and functional groups make it a versatile starting material for the development of new molecules with specific properties and applications.
Used in Research and Development:
Due to its unique chemical structure, 3-Ethylaminophenol is often utilized in research and development for the study of chemical reactions, mechanisms, and the development of new synthetic methods. It can serve as a model compound for understanding the behavior of similar aromatic amines and their interactions with other molecules.
Air & Water Reactions
3-ETHYLAMINOPHENOL may be sensitive to prolonged exposure to air. . Slightly soluble in water.
Reactivity Profile
An amine and phenol. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Phenols do not behave as organic alcohols, as one might guess from the presence of a hydroxyl (-OH) group in their structure. Instead, they react as weak organic acids. Phenols and cresols are much weaker as acids than common carboxylic acids (phenol has Ka = 1.3 x 10^[-10]). These materials are incompatible with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides. Flammable gas (H2) is often generated, and the heat of the reaction may ignite the gas. Heat is also generated by the acid-base reaction between phenols and bases. Such heating may initiate polymerization of the organic compound. Phenols are sulfonated very readily (for example, by concentrated sulfuric acid at room temperature). The reactions generate heat. Phenols are also nitrated very rapidly, even by dilute nitric acid.
Fire Hazard
Flash point data for 3-ETHYLAMINOPHENOL are not available, however, 3-ETHYLAMINOPHENOL is probably combustible.
Check Digit Verification of cas no
The CAS Registry Mumber 621-31-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,2 and 1 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 621-31:
(5*6)+(4*2)+(3*1)+(2*3)+(1*1)=48
48 % 10 = 8
So 621-31-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H11NO/c1-2-9-7-4-3-5-8(10)6-7/h3-6,9-10H,2H2,1H3
621-31-8Relevant articles and documents
OXAZINE-BASED WATER-SOLUBLE FLUOROPHORE COMPOUNDS FOR IN VIVO NERVE IMAGING
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Page/Page column 36-38, (2021/07/10)
This invention provides novel oxazine-based, water soluble fluorophore compounds useful in in vivo nerve imaging, as well as compositions comprising them and methods for their use.
NEAR-INFRARED NERVE-SPARING FLUOROPHORES
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Page/Page column 41-42, (2020/02/17)
Provided are far red to near-infrared nerve-sparing fluorescent compounds, compositions comprising them, and methods of their use in medical procedures.
Structural modifications of nile red carbon monoxide fluorescent probe: Sensing mechanism and applications
Klán, Petr,Madea, Dominik,Martínek, Marek,Muchová, Lucie,Váňa, Ji?í,Vítek, Libor
, p. 3473 - 3489 (2020/03/25)
Carbon monoxide (CO) is a cell-signaling molecule (gasotransmitter) produced endogenously by oxidative catabolism of heme, and the understanding of its spatial and temporal sensing at the cellular level is still an open challenge. Synthesis, optical properties, and study of the sensing mechanism of Nile red Pd-based CO chemosensors, structurally modified by core and bridge substituents, in methanol and aqueous solutions are reported in this work. The sensing fluorescence "off-on" response of palladacycle-based sensors possessing low-background fluorescence arises from their reaction with CO to release the corresponding highly fluorescent Nile red derivatives in the final step. Our mechanistic study showed that electron-withdrawing and electron-donating core substituents affect the rate-determining step of the reaction. More importantly, the substituents were found to have a substantial effect on the Nile red sensor fluorescence quantum yields, hereby defining the sensing detection limit. The highest overall fluorescence and sensing rate enhancements were found for a 2-hydroxy palladacycle derivative, which was used in subsequent biological studies on mouse hepatoma cells as it easily crosses the cell membrane and qualitatively traces the localization of CO within the intracellular compartment with the linear quantitative response to increasing CO concentrations.
