61854-36-2

Basic information

• Product Name: DeMethoxycapillarisin
• Synonyms: DeMethoxycapillarisin
• CAS NO: 61854-36-2
• Molecular Formula: C₁₅H₁₀O₆
• Molecular Weight: 286.2363
• Mol File: 61854-36-2.mol
• Article Data: 1

Chemical Properties

• Melting Point: >280 °C (decomp)
• Boiling Point: 535.9°Cat760mmHg
• Flash Point: 207.5°C
• Appearance: /
• Density: 1.591g/cm³
• Vapor Pressure: 4.24E-12mmHg at 25°C
• Refractive Index: 1.728
• PKA: 6.39±0.40(Predicted)
• CAS DataBase Reference: DeMethoxycapillarisin(CAS DataBase Reference)
• NIST Chemistry Reference: DeMethoxycapillarisin(61854-36-2)
• EPA Substance Registry System: DeMethoxycapillarisin(61854-36-2)

Safety Data

• Hazardous Substances Data: 61854-36-2(Hazardous Substances Data)

Usage

Description

DeMethoxycapillarisin is a flavonoid derivative found in the Artemisia capillaris Thunberg, a plant widely used in traditional Chinese medicine. It exhibits various biological activities, such as anti-inflammatory, anti-oxidative, and hepatoprotective effects, making it a promising compound for therapeutic applications.
Used in Pharmaceutical Industry:
DeMethoxycapillarisin is used as a therapeutic agent for the treatment of liver diseases, as it effectively reduces hepatic inflammation and oxidative stress, thereby protecting the liver from damage.
Used in Anticancer Applications:
DeMethoxycapillarisin is used as an anticancer agent, showing potential in inhibiting the growth of cancer cells. Its pharmacological activities make it a promising candidate for further research and development in cancer treatment.
Used in Traditional Chinese Medicine:
DeMethoxycapillarisin is used as a key component in traditional Chinese medicine formulations, leveraging its anti-inflammatory, anti-oxidative, and hepatoprotective properties to treat various health conditions.

InChI:InChI=1/C15H10O6/c16-8-1-3-10(4-2-8)20-14-7-12(19)15-11(18)5-9(17)6-13(15)21-14/h1-7,16-18H

Upstream product

• 78899-33-9 3-[2,4-Dimethoxy-6-(4-methoxy-phenoxycarbonyloxy)-phenyl]-3-oxo-2-(triphenyl-λ⁵-phosphanylidene)-propionic acid benzyl ester 
• 78899-42-0 5,7-Dimethoxy-2-(4-methoxy-phenoxy)-4-oxo-4H-chromene-3-carboxylic acid benzyl ester 
• 78899-17-9 2,4-Dimethoxy-6-(4-methoxy-phenoxycarbonyloxy)-benzoic acid benzyl ester 
• 78899-51-1 5,7-Dimethoxy-2-(4-methoxy-phenoxy)-4-oxo-4H-chromene-3-carboxylic acid 
• 78899-25-9 2,4-Dimethoxy-6-(4-methoxy-phenoxycarbonyloxy)-benzoic acid 
• 64964-85-8 5,7-dimethoxy-2-(4-methoxy-phenoxy)-chromen-4-one 

Downstream Products

• 61854-32-8 5-Hydroxy-7-methoxy-2-(4-methoxy-phenoxy)-chromen-4-one 

Relevant articles and documents

Synthesis of Demethoxycapillarisin, a Naturally Occurring 2-Phenoxychromone, and Related Compounds

Demethoxycapillarisin (1), a naturally occurring 2-phenoxychromone, and the related compounds (2) - (4) have been synthesized via a route involving, as a key step, an intramolecular Wittig reaction between a phosphorus ylide and a carbonate.