6171-48-8 Usage
Description
4-Methylestradiol, also known as Estradiol EP Impurity C, is an impurity of Estradiol (E888000). It is a synthetic compound derived from the modification of the natural hormone estradiol, which is a primary female sex hormone.
Used in Pharmaceutical Industry:
4-Methylestradiol is used as an impurity reference standard for the quality control and testing of Estradiol products. It helps ensure the purity, potency, and safety of Estradiol medications, which are used for hormone replacement therapy, contraception, and treatment of various conditions related to hormonal imbalances.
Used in Research Applications:
4-Methylestradiol is used as a research tool in scientific studies to investigate the effects of impurities on the biological activity and safety of Estradiol. This helps in understanding the potential risks and side effects associated with the presence of impurities in pharmaceutical products and aids in the development of better quality control measures.
Check Digit Verification of cas no
The CAS Registry Mumber 6171-48-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,1,7 and 1 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 6171-48:
(6*6)+(5*1)+(4*7)+(3*1)+(2*4)+(1*8)=88
88 % 10 = 8
So 6171-48-8 is a valid CAS Registry Number.
InChI:InChI=1/C19H26O2/c1-11-12-3-4-15-14(13(12)5-7-17(11)20)9-10-19(2)16(15)6-8-18(19)21/h5,7,14-16,18,20-21H,3-4,6,8-10H2,1-2H3/t14-,15-,16+,18+,19+/m1/s1
6171-48-8Relevant articles and documents
Cross-coupling of [11C]methyllithium for 11C-labelled PET tracer synthesis
Helbert, Hugo,Antunes, Ines Farinha,Luurtsema, Gert,Szymanski, Wiktor,Feringa, Ben L.,Elsinga, Philip H.
supporting information, p. 203 - 206 (2021/01/13)
The cross-coupling of aryl bromides with [11C]CH3Li for the labelling of a variety of tracers for positron emission tomography (PET) is presented. The radiolabelled products were obtained in excellent yields, at rt and after short reaction times (3-5 min) compatible with the half-life of 11C (20.4 min). The automation of the protocol on a synthesis module is investigated, representing an important step towards a fast method for the synthesis of 11C-labelled compounds for PET imaging. This journal is
THE SYNTHESIS OF 2- AND 4-ALKOXYMETHYLESTROGENS.
KANEKO,HASHIMOTO,KOBAYASHI
, p. 196 - 203 (2007/10/06)
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