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  • 615-60-1 Structure
  • Basic information

    1. Product Name: 4-Chloro-1,2-dimethylbenzene
    2. Synonyms: 4-Chloro-ortho-xylene;o-Xylene, 4-chloro-;4-CHLORO-1,2-XYLENE;4-CHLORO-1,2-DIMETHYLBENZENE;4-CHLORO-O-XYLENE;3,4-DIMETHYLCHLOROBENZENE;1-CHLORO-3,4-DIMETHYLBENZENE;CHLORO-1,2-DIMETHYLBENZENE
    3. CAS NO:615-60-1
    4. Molecular Formula: C8H9Cl
    5. Molecular Weight: 140.61
    6. EINECS: 210-438-6
    7. Product Categories: Aromatic Hydrocarbons (substituted) & Derivatives;Halogen toluene;Chlorine Compounds
    8. Mol File: 615-60-1.mol
    9. Article Data: 16
  • Chemical Properties

    1. Melting Point: -6°C
    2. Boiling Point: 221-223 °C(lit.)
    3. Flash Point: 152 °F
    4. Appearance: Clear colorless/Liquid
    5. Density: 1.047 g/mL at 25 °C(lit.)
    6. Vapor Pressure: 0.685mmHg at 25°C
    7. Refractive Index: n20/D 1.528(lit.)
    8. Storage Temp.: 2-8°C
    9. Solubility: Chloroform (Slightly), Methanol (Slightly)
    10. Water Solubility: 27mg/L at 26℃
    11. BRN: 2076514
    12. CAS DataBase Reference: 4-Chloro-1,2-dimethylbenzene(CAS DataBase Reference)
    13. NIST Chemistry Reference: 4-Chloro-1,2-dimethylbenzene(615-60-1)
    14. EPA Substance Registry System: 4-Chloro-1,2-dimethylbenzene(615-60-1)
  • Safety Data

    1. Hazard Codes: Xi,Xn
    2. Statements: 36/37/38-20/21
    3. Safety Statements: 26-36-36/37-23
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 615-60-1(Hazardous Substances Data)

615-60-1 Usage

Description

4-Chloro-1,2-dimethylbenzene, also known as Durene, is an organic compound belonging to the aromatic hydrocarbon family. It is characterized by its clear colorless to light yellow liquid appearance and is known for its distinct chemical properties.

Uses

Used in Biochemical Applications:
4-Chloro-1,2-dimethylbenzene is used as an inhibitor for TDG (Tet methylcytosine dioxygenase) activity. This application is particularly relevant in the field of epigenetics, where it can help regulate gene expression by modulating the activity of TDG enzymes.
Used in Chemical Synthesis:
In the chemical industry, 4-Chloro-1,2-dimethylbenzene can be utilized as a starting material or intermediate in the synthesis of various organic compounds, taking advantage of its unique chemical structure and reactivity.
Used in Solvent Applications:
Due to its liquid state and chemical stability, 4-Chloro-1,2-dimethylbenzene can be employed as a solvent in various chemical processes, facilitating reactions and improving the efficiency of certain industrial applications.
Used in Pharmaceutical Research:
4-Chloro-1,2-dimethylbenzene may also find use in the pharmaceutical sector, particularly in drug discovery and development. Its unique chemical properties could make it a valuable tool in the design and synthesis of new therapeutic agents.

Flammability and Explosibility

Nonflammable

Check Digit Verification of cas no

The CAS Registry Mumber 615-60-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,1 and 5 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 615-60:
(5*6)+(4*1)+(3*5)+(2*6)+(1*0)=61
61 % 10 = 1
So 615-60-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H9Cl/c1-6-3-4-8(9)5-7(6)2/h3-5H,1-2H3

615-60-1 Well-known Company Product Price

  • Brand
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  • Alfa Aesar

  • (A19032)  4-Chloro-o-xylene, 98%   

  • 615-60-1

  • 10g

  • 183.0CNY

  • Detail
  • Alfa Aesar

  • (A19032)  4-Chloro-o-xylene, 98%   

  • 615-60-1

  • 25g

  • 348.0CNY

  • Detail
  • Alfa Aesar

  • (A19032)  4-Chloro-o-xylene, 98%   

  • 615-60-1

  • 50g

  • 456.0CNY

  • Detail
  • Alfa Aesar

  • (A19032)  4-Chloro-o-xylene, 98%   

  • 615-60-1

  • 100g

  • 812.0CNY

  • Detail

615-60-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 3,4-Dimethylchlorobenzene

1.2 Other means of identification

Product number -
Other names Benzene, 4-chloro-1,2-dimethyl-

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:615-60-1 SDS

615-60-1Relevant articles and documents

Synthetic method of 1-(4-iodophenyl)-5-chlorinisobenzofuran

-

Paragraph 0007, (2016/10/27)

The invention relates to a synthetic method of a compound, in particular to a synthetic method of 1-(4-iodophenyl)-5-chlorinisobenzofuran.By means of the method, the 1-(4-iodophenyl)-5-chlorinisobenzofuran is obtained through a series of reactions of oxidation, condensation and the like.The method is mild in reaction condition and high in yield.

Microwave assisted solid additive effects in simple dry chlorination reactions with n-chlorosuccinimide

Bucos, Madalina,Villalonga-Barber, Carolina,Micha-Screttas, Maria,Steele, Barry R.,Screttas, Constantinos G.,Heropoulos, Georgios A.

experimental part, p. 2061 - 2065 (2010/04/26)

Solid additives participate in the dry microwave assisted chlorination reaction of N-chlorosuccinimide with the xylenes affecting both yields and chemoselectivities. Total yields can be increased up to nine times for simple alkylaromatics and chemoselectivities can be altered according to the desired ring or α-side chlorination product by choosing the appropriate additive. We believe that in these reactions the solid additives play a very important role by increasing yields and affecting chemoselectivities, as well as behaving as microwave energy absorbers that consequently aid the transfer of heat to the active reagents.

Chlorination of aromatic substrates catalyzed by the phthalocyanine complexes

Ivanov,Tsentalovich,Kogan,Tomilova,Zefirov

experimental part, p. 1676 - 1679 (2011/04/23)

The chlorination of benzene, toluene, and o-xylene with molecular chlorine in the presence of the phthalocyanine complexes of different structures was studied. The transformations of the catalysts during the reaction were investigated.

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