6141-13-5 Usage
Description
2-Chloroquinazoline, with the molecular formula C8H6ClN2, is a heterocyclic compound characterized by a quinazoline ring that incorporates a chlorine atom. It is recognized for its diverse applications in organic synthesis and pharmaceutical development, making it a valuable intermediate in the creation of pharmaceuticals, agrochemicals, and fine chemicals. Moreover, 2-Chloroquinazoline demonstrates antiproliferative and cytotoxic properties, positioning it as a candidate for cancer treatment research. Its utility extends to the synthesis of other biologically active compounds, highlighting its versatility in the pharmaceutical and chemical industries.
Uses
Used in Pharmaceutical Development:
2-Chloroquinazoline is used as an intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Agrochemical Synthesis:
In the agrochemical industry, 2-Chloroquinazoline serves as a key intermediate, aiding in the production of compounds designed to protect crops and enhance agricultural yields.
Used in Fine Chemicals Production:
2-Chloroquinazoline is utilized in the synthesis of fine chemicals, which are high-purity chemicals used in various applications, including research, pharmaceuticals, and specialty industries.
Used in Cancer Treatment Research:
2-Chloroquinazoline is used as a research compound in cancer treatment studies due to its antiproliferative and cytotoxic effects, which may lead to the discovery of novel anticancer therapies.
Used in Organic Synthesis as a Building Block:
As a versatile building block in organic synthesis, 2-Chloroquinazoline is employed in the creation of other biologically active compounds, expanding its utility across various chemical and pharmaceutical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 6141-13-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,1,4 and 1 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 6141-13:
(6*6)+(5*1)+(4*4)+(3*1)+(2*1)+(1*3)=65
65 % 10 = 5
So 6141-13-5 is a valid CAS Registry Number.
InChI:InChI=1/C8H5ClN2/c9-8-10-5-6-3-1-2-4-7(6)11-8/h1-5H
6141-13-5Relevant articles and documents
SUBSTITUTED QUINAZOLINES
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, (2008/06/13)
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Pyrolysis of 1-substituted pyrazoles and chloroform at 550°C: Formation of α-carboline from 1-benzylpyrazoles
Bhatti, Inayat A.,Busby, Reginald E.,Bin Mohamed, Murtedza,Parrick, John,Shaw, C. J. Granville
, p. 3581 - 3585 (2007/10/03)
Pyrolysis of 13CH3 labelled 1-methylpyrazole 8 with chloroform at 550°C in a continuous flow reactor yields unlabelled 2-chloropyrimidine 9 and 2-cyanopyrrole 10 labelled at the cyano group. However, pyrolysis of 1-benzylpyrazole 14 with chloroform under similar conditions gives 9,2-phenylpyrimidine 13 and, as the major product, α-carboline 15. Pyrolysis of several substituted 1-(arylmethyl)pyrazoles and the use of 13C and 15N labelled compounds provides direct evidence by which the positions of 7 atoms of 1-benzylpyrazole can be located in the α-carboline. These data support the mechanisms suggested for the formation of 9, 10, and 15.