61372-79-0

Basic information

• Product Name: 1-(3-nitrophenyl)pyrrolidin-2-one
• Synonyms: 1-(3-nitrophenyl)pyrrolidin-2-one
• CAS NO: 61372-79-0
• Molecular Formula: C₁₀H₁₀N₂O₃
• Molecular Weight: 206.198
• Mol File: 61372-79-0.mol
• Article Data: 13

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-(3-nitrophenyl)pyrrolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-nitrophenyl)pyrrolidin-2-one(61372-79-0)
• EPA Substance Registry System: 1-(3-nitrophenyl)pyrrolidin-2-one(61372-79-0)

Safety Data

• Hazardous Substances Data: 61372-79-0(Hazardous Substances Data)

Usage

Description

1-(3-nitrophenyl)pyrrolidin-2-one is a heterocyclic chemical compound with a molecular formula C11H10N2O3. It belongs to the pyrrolidin-2-one class of chemicals and features a nitrophenyl group. 1-(3-nitrophenyl)pyrrolidin-2-one has been studied for its potential medicinal properties, particularly as an anti-inflammatory and analgesic agent. Its unique chemical structure and properties also make it a candidate for use in pharmaceuticals and agrochemicals, highlighting its versatility in various fields of chemistry and medicine.

Uses

Used in Pharmaceutical Industry:
1-(3-nitrophenyl)pyrrolidin-2-one is used as a medicinal compound for its potential anti-inflammatory and analgesic properties, offering a promising therapeutic option for the treatment of pain and inflammation.
Used in Agrochemical Industry:
1-(3-nitrophenyl)pyrrolidin-2-one is utilized as a chemical constituent in agrochemicals, leveraging its unique structure and properties to contribute to the development of effective products for agricultural applications.

Upstream product

• 616-45-5 2-pyrrolidinon 
• 121-73-3 3-Nitrochlorobenzene 
• 585-79-5 m-nitrobromobenzene 
• 645-00-1 m-iodonitrobenzene 
• 304684-54-6 4-chloro-N-(3-nitrophenyl)butanamide 
• 13331-27-6 m-nitrobenzene boronic acid 
• 99-09-2 3-nitro-aniline 
• 4635-59-0 4-Chlorobutanoyl chloride 
• 27969-73-9 1‐(3‐nitrophenyl)piperidine 

Downstream Products

• 31992-43-5 1-(3-aminophenyl)pyrrolidin-2-one 
• 344312-54-5 3-(2-oxopyrrolidin-1-yl)benzene-1-sulfonyl chloride 

Relevant articles and documents

Synthetic method of N - aryl substituted lactam compound

The invention discloses a method. NSynthesis method of - aryl substituted lactam compound, and synthesis method thereof is promoted by tertiary butyl hydroperoxide and-tert-butyl hydroperoxideNMulti-step series reaction synthesis - aryl substituted saturated cyclic amine compoundN- Aryl substituted lactam compounds are simple and convenient to operate. The method has the advantages of no transition metal catalysis, wide substrate application range and the like, and is suitable for industrial production.

Aluminium Chloride-Mediated Synthesis of 1-Chloro-2,2,2-Trifluoroethylidene-Substituted Pyrrolidones

An aluminium chloride-mediated cascade reaction between pyrrolidones and trifluoroacetic anhydride is reported. Functionally diverse 1-chloro-2,2,2-trifluoroethylidene-substituted pyrrolidones were obtained in moderate to high yields through electrophilic trifluoroacetylation, nucleophilic chlorination, and elimination. This procedure has a wide scope, good functional-group tolerance and the reaction conditions are amenable to scale up. Additionally the obtained 1-chloro-2,2,2-trifluoroethylidene products can be applied to further functionalization as trifluoromethyl-containing building blocks. Some of the title compounds showed fungicidal activity against cucumber downy mildew (CDM). (Figure presented.).

Selective copper-catalyzed N-arylation of lactams with arylboronic acids under base- and ligand-free conditions

An oxidative copper-catalyzed cross-coupling of arylboronic acids with various ring-size lactams has been developed. The N-arylated lactams were obtained in moderate to excellent yields without any additional bases, ligands, or additives. This reaction shows complete selectivity for N-arylation of lactams in the presence of a hydroxyl group.