6125-63-9 Usage
Description
(E)-3-(2-furyl)acrylonitrile, with the molecular formula C7H5NO, is a yellow liquid chemical compound characterized by a strong, sweet, and nutty odor. It is known for its versatile applications in various industries, including the production of perfumes, pharmaceuticals, and other organic chemicals. Additionally, it serves as a precursor in organic synthesis reactions, particularly in the formation of heterocyclic compounds. However, it is considered a hazardous chemical, necessitating careful handling and storage to prevent irritation to the skin, eyes, and respiratory system.
Uses
Used in Perfume Industry:
(E)-3-(2-furyl)acrylonitrile is used as a fragrance ingredient for its strong, sweet, and nutty odor, contributing to the creation of various perfumes and scented products.
Used in Pharmaceutical Industry:
(E)-3-(2-furyl)acrylonitrile is used as a building block in the synthesis of pharmaceutical compounds, playing a crucial role in the development of new drugs and medications.
Used in Organic Chemicals Production:
(E)-3-(2-furyl)acrylonitrile is used as a raw material in the production of various organic chemicals, contributing to the synthesis of a wide range of chemical products.
Used in Organic Synthesis Reactions:
(E)-3-(2-furyl)acrylonitrile is used as a precursor in organic synthesis reactions, particularly in the formation of heterocyclic compounds, which are important in the development of new chemical entities and materials.
Safety Precautions:
Due to its hazardous nature, (E)-3-(2-furyl)acrylonitrile requires careful handling and storage to minimize exposure and potential health risks. It is essential to follow safety regulations and guidelines to ensure the well-being of individuals working with this compound.
Check Digit Verification of cas no
The CAS Registry Mumber 6125-63-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,1,2 and 5 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 6125-63:
(6*6)+(5*1)+(4*2)+(3*5)+(2*6)+(1*3)=79
79 % 10 = 9
So 6125-63-9 is a valid CAS Registry Number.
6125-63-9Relevant articles and documents
Preparation method of nitrile compound
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Paragraph 0072-0074, (2022/01/08)
The present invention belongs to the field of organic synthesis technology, specifically relates to a method for preparing a nitrile compound, aldehyde oxime derivatives as raw materials, adding DPPA and DBU, reacting in an organic solvent, one step to pr
Development and Utilization of a Palladium-Catalyzed Dehydration of Primary Amides to Form Nitriles
Al-Huniti, Mohammed H.,Rivera-Chávez, José,Colón, Katsuya L.,Stanley, Jarrod L.,Burdette, Joanna E.,Pearce, Cedric J.,Oberlies, Nicholas H.,Croatt, Mitchell P.
supporting information, p. 6046 - 6050 (2018/09/27)
A palladium(II) catalyst, in the presence of Selectfluor, enables the efficient and chemoselective transformation of primary amides into nitriles. The amides can be attached to aromatic rings, heteroaromatic rings, or aliphatic side chains, and the reactions tolerate steric bulk and electronic modification. Dehydration of a peptaibol containing three glutamine groups afforded structure-activity relationships for each glutamine residue. Thus, this dehydration can act similarly to an alanine scan for glutamines via synthetic mutation.
One-Pot Synthesis of α,β-Unsaturated Esters, Ketones, and Nitriles from Alcohols and Phosphonium Salts
Ding, Weijie,Hu, Juan,Jin, Huile,Yu, Xiaochun,Wang, Shun
, p. 107 - 118 (2017/09/28)
A general method for the synthesis of α,β-unsaturated esters, ketones, and nitriles is successfully achieved by a one-pot copper-catalyzed oxidation with O 2 in air as oxidant. The solvent mixture of acetonitrile and formamide (1:1) is optimized to ensure the oxidation of alcohols, deprotonation of phosphonium salt, and Wittig reaction occur efficiently in one pot. A broad range of substrates has been explored for this process, including three electron-withdrawing group (CO 2 Et, COPh, CN) functionalized phosphonium salts. They reacted not only with benzylic and heteroaromatic alcohols, but also with aliphatic alcohols, forming the corresponding α,β-unsaturated esters, ketones, and nitriles in moderate to excellent yields.
