6099-23-6Relevant articles and documents
Photoredox-Mediated Synthesis of Functionalized Sulfoxides from Terminal Alkynes
Kumar, Jaswant,Ahmad, Ajaz,Rizvi, Masood Ahmad,Ganie, Majid Ahmed,Khajuria, Chhavi,Shah, Bhahwal Ali
supporting information, p. 5661 - 5665 (2020/07/14)
A photoredox-mediated protocol for the synthesis of α-alkoxy-β-ketosulfoxides and α,β-dialkoxysulfoxides using alkynes, thiol, and alcohols is reported. This work presents a rare single-step synthesis of α-substituted sulfoxides, involving tandem introduction of a thiol and alcohol as a key enabling advancement. Furthermore, the method can be easily employed to access vinyl sulfoxides and β-ketosulfoxides.
Stereochemical analysis of β-keto sulfoxides by circular dichroism
Górecki, Marcin,Capozzi, Maria Annunziata M.,Albano, Gianluigi,Cardellicchio, Cosimo,Di Bari, Lorenzo,Pescitelli, Gennaro
, p. 29 - 42 (2017/11/13)
Three β-keto sulfoxides (1–3) were synthesized in enantiopure form and investigated by means of circular dichroism (CD) spectroscopy, both in electronic and vibrational range (ECD, VCD), in combination with quantum chemical calculations. For compound 2, t
Acid-Catalyzed Oxidative Addition of Thiols to Olefins and Alkynes for a One-Pot Entry to Sulfoxides
Yue, Hui-Lan,Klussmann, Martin
supporting information, p. 2505 - 2509 (2016/10/24)
An oxidative variant of the thiol-ene reaction has been developed, achieving the direct addition of thiols to olefins to form sulfoxides. The reaction uses tert-butyl hydroperoxide as oxidant and methanesulfonic acid as catalyst. The latter is believed to catalyze the oxidation of the intermediate sulfide to the sulfoxide. No special precautions are necessary to exclude oxygen, yet the products are formed without oxidation at the β-position. Styrenes, acrylic acid derivatives, alkynes, and thiophenols gave the highest yields, while aliphatic olefins and thiols were less effective.