60764-18-3

Basic information

• Product Name: Pyridinium, 3-[(hydroxyimino)methyl]-1-(phenylmethyl)-, bromide
• CAS NO: 60764-18-3
• Molecular Formula: C13H13N2O.Br
• Molecular Weight: 293.163
• Mol File: 60764-18-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Pyridinium, 3-[(hydroxyimino)methyl]-1-(phenylmethyl)-, bromide(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridinium, 3-[(hydroxyimino)methyl]-1-(phenylmethyl)-, bromide(60764-18-3)
• EPA Substance Registry System: Pyridinium, 3-[(hydroxyimino)methyl]-1-(phenylmethyl)-, bromide(60764-18-3)

Safety Data

• Hazardous Substances Data: 60764-18-3(Hazardous Substances Data)

Usage

General Description

Pyridinium, 3-[(hydroxyimino)methyl]-1-(phenylmethyl)-, bromide is a chemical compound that consists of a pyridinium ring with a phenylmethyl group and a hydroxyimino moiety attached. It is commonly used in laboratory research as a reagent for organic synthesis reactions, particularly as a catalyst or intermediate in the preparation of various organic compounds. The bromide ion attached to the pyridinium ring enhances its reactivity and solubility in polar solvents, making it useful in a wide range of chemical processes. The compound's unique structure and properties make it valuable for applications in pharmaceuticals, agrochemicals, and material science. Additionally, it is important to handle this chemical with care due to its potential hazards and toxicity.

Upstream product

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Relevant articles and documents

New safe method for preparation of sarin-exposed human erythrocytes acetylcholinesterase using non-toxic and stable sarin analogue isopropyl p-nitrophenyl methylphosphonate and its application to evaluation of nerve agent antidotes

Introduction. A non-toxic and stable sarin analogue, isopropyl p-nitrophenyl methylphosphonate (INMP), was synthesized for safe preparation of sarin-exposed acetylcholinesterase (AChE). Results and Discussion. This agent was stable for years, able to be handled in an ordinary laboratory without special care, and its 50% inhibitory concentration (IC50) on 0.04 U/ml human erythrocytes AChE was 15 nM. This reagent was thought to be especially useful since it enables experiments that require sarin-inhibited AChE, such as the development of antidotes for sarin, in a usual laboratory. To demonstrate the usefulness of this method, 40 known and novel pyridinealdoxime methiodide (PAM)-type oxime antidotes were synthesized, and their reactivation activities to INMP-exposed AChE and structure-activities correlation were studied. Conclusion. Among the antidotes tested in this experiment except for 2-PAM, the compound found to have the highest reactivation activity, was the novel hydrophobic 2-PAM-type compound, 2-[(hydroxyimino)methyl]-1-[4-(tert- butyl)benzyl] pyridinium bromide.

The reaction of quaternary pyridine derivatives with imidazoles.

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