606922-11-6Relevant articles and documents
Antitumor agents. Part 226: Synthesis and cytotoxicity of 2-phenyl-4-quinolone acetic acids and their esters
Xia, Yi,Yang, Zheng-Yu,Xia, Peng,Bastow, Kenneth F.,Nakanishi, Yuka,Nampoothiri, Priya,Hamel, Ernest,Brossi, Arnold,Lee, Kuo-Hsiung
, p. 2891 - 2893 (2007/10/03)
2-Phenyl-4-quinolone acetic acids and their esters were synthesized and evaluated for interaction with tubulin and for cytotoxicity against a panel of human tumor cell lines. 2-Phenyl- and 2-(2′-fluorophenyl)-4-quinolone-8- acetic acids (11 and 12) displa