6052-64-8 Usage
Description
1,1,4-triphenylbut-3-en-1-ol is a chemical compound belonging to the phenol family, characterized by its molecular formula C22H20O. It is a white solid with a melting point of approximately 174-176°C and is insoluble in water. 1,1,4-triphenylbut-3-en-1-ol features a butenolide core with three phenyl groups attached, which endows it with distinctive physical and chemical properties. Its reactivity and versatility in chemical transformations make it a valuable building block in the synthesis of various organic compounds and pharmaceuticals.
Uses
Used in Organic Synthesis:
1,1,4-triphenylbut-3-en-1-ol is used as a building block for the synthesis of various organic compounds and pharmaceuticals due to its unique structure and reactivity.
Used in Pharmaceutical Industry:
1,1,4-triphenylbut-3-en-1-ol is used as a key intermediate in the development of pharmaceuticals, contributing to the creation of new drugs and therapeutic agents.
Used in Chemical Research:
1,1,4-triphenylbut-3-en-1-ol is utilized in chemical research for studying reaction mechanisms and exploring new synthetic pathways, further expanding the scope of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 6052-64-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,0,5 and 2 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 6052-64:
(6*6)+(5*0)+(4*5)+(3*2)+(2*6)+(1*4)=78
78 % 10 = 8
So 6052-64-8 is a valid CAS Registry Number.
6052-64-8Relevant articles and documents
Zinc-mediated α-regioselective Barbier-type cinnamylation reactions of aldehydes, ketones and esters
Zhao, Li-Ming,Gao, Hua-Shuai,Li, De-Feng,Dong, Jing,Sang, Lan-Lin,Ji, Jie
, p. 4359 - 4366 (2017/07/10)
We report a simple, efficient, and general method for the zinc-mediated regioselective cinnamylation of aldehydes and ketones under Barbier-type conditions in a one-pot synthesis affording the corresponding α-cinnamylated alcohols in moderate to excellent yields. Compared to the literature procedures, this approach is operationally simple, uses simple reactants, and provides direct access to linear α-cinnamylated alcohols with excellent regioselectivity. Experimental results suggest that the reactions proceed through the radical pathway. In addition, the reaction was found to be scalable to the gram-scale and the one-pot protocol is also applicable to less reactive esters leading to bishomoallylic alcohols which were valuable intermediates for desymmetrizing intramolecular Heck cyclization, allowing for the elaboration to functionalized building blocks.
α-Regioselective Barbier Reaction of Carbonyl Compounds and Allyl Halides Mediated by Praseodymium
Wu, San,Li, Ying,Zhang, Songlin
, p. 8070 - 8076 (2016/09/09)
The first utility of praseodymium as a mediating metal in the Barbier reaction of carbonyl compounds with allyl halides was reported in this paper. In contrast to the traditional metal-mediated or catalyzed Barbier reactions, exclusive α-adducts were obta
