6034-54-4 Usage
Description
Sodium N-acetylsulphanilate, a sodium salt of N-acetylsulphanilate derived from sulfanilic acid, is a versatile chemical compound with a broad spectrum of applications, particularly in the pharmaceutical and agrochemical industries. It serves as an essential intermediate in the synthesis of various drugs, medications, dyes, and pigments. Known for its anti-inflammatory and analgesic properties, sodium N-acetylsulphanilate may contribute to the treatment of specific medical conditions, making it a valuable component in the development of pharmaceutical products.
Uses
Used in Pharmaceutical Industry:
Sodium N-acetylsulphanilate is used as an intermediate in the synthesis of various drugs and medications for its ability to facilitate the production of a wide range of pharmaceutical products.
Used in Agrochemical Industry:
Sodium N-acetylsulphanilate is used as an intermediate in the production of agrochemicals, contributing to the development of various agricultural products.
Used in Dye and Pigment Production:
Sodium N-acetylsulphanilate is used as a key component in the manufacturing process of dyes and pigments, enabling the creation of a diverse array of colorants for various applications.
Used in Medical Treatments:
Sodium N-acetylsulphanilate is used as an anti-inflammatory and analgesic agent for its potential role in treating certain medical conditions, providing relief and support for patients in need.
Check Digit Verification of cas no
The CAS Registry Mumber 6034-54-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,0,3 and 4 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 6034-54:
(6*6)+(5*0)+(4*3)+(3*4)+(2*5)+(1*4)=74
74 % 10 = 4
So 6034-54-4 is a valid CAS Registry Number.
InChI:InChI=1/C8H9NO4S.Na/c1-6(10)9-7-2-4-8(5-3-7)14(11,12)13;/h2-5H,1H3,(H,9,10)(H,11,12,13);/q;+1/p-1
6034-54-4Relevant articles and documents
Beyond Basicity: Discovery of Nonbasic DENV-2 Protease Inhibitors with Potent Activity in Cell Culture
Kühl, Nikos,Leuthold, Mila M.,Behnam, Mira A. M.,Klein, Christian D.
supporting information, p. 4567 - 4587 (2021/05/06)
The viral serine protease NS2B-NS3 is one of the promising targets for drug discovery against dengue virus and other flaviviruses. The molecular recognition preferences of the protease favor basic, positively charged moieties as substrates and inhibitors, which leads to pharmacokinetic liabilities and off-target interactions with host proteases such as thrombin. We here present the results of efforts that were aimed specifically at the discovery and development of noncharged, small-molecular inhibitors of the flaviviral proteases. A key factor in the discovery of these compounds was a cellular reporter gene assay for the dengue protease, the DENV2proHeLa system. Extensive structure-activity relationship explorations resulted in novel benzamide derivatives with submicromolar activities in viral replication assays (EC50 0.24 μM), selectivity against off-target proteases, and negligible cytotoxicity. This structural class has increased drug-likeness compared to most of the previously published active-site-directed flaviviral protease inhibitors and includes promising candidates for further preclinical development.
