60174-89-2

Basic information

• Product Name: 1-(3,5-bis(trifluoromethyl)phenyl)cyclohexan-1-ol
• Synonyms: 1-(3,5-bis(trifluoromethyl)phenyl)cyclohexan-1-ol
• CAS NO: 60174-89-2
• Molecular Weight: 312.255
• Mol File: 60174-89-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(3,5-bis(trifluoromethyl)phenyl)cyclohexan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3,5-bis(trifluoromethyl)phenyl)cyclohexan-1-ol(60174-89-2)
• EPA Substance Registry System: 1-(3,5-bis(trifluoromethyl)phenyl)cyclohexan-1-ol(60174-89-2)

Safety Data

• Hazardous Substances Data: 60174-89-2(Hazardous Substances Data)

Upstream product

• 328-70-1 3,6-bis(trifluoromethyl)bromobenzene 
• 108-94-1 cyclohexanone 
• 75-89-8 2,2,2-trifluoroethanol 
• 162780-93-0 <1-<3,5-Bis(trifluoromethyl)phenyl>cyclopentyl>carbinyl tosylate 
• 112981-69-8 3,5-bis(trifluoromethyl)phenylmagnesium bromide 

Relevant articles and documents

Triphosgene and DMAP as Mild Reagents for Chemoselective Dehydration of Tertiary Alcohols

The utility of triphosgene and DMAP as mild reagents for chemoselective dehydration of tertiary alcohols is reported. Performed in dichloromethane at room temperature, this reaction is readily tolerated by a broad scope of substrates, yielding alkenes preferentially with the (E)-geometry. While formation of the Hofmann products is generally favored, a dramatic change in alkene selectivity toward the Zaitzev products is observed when the reaction is carried out in dichloroethane at reflux.