599-64-4

Basic information

• Product Name: p-Cumylphenol
• Synonyms: Phenol, p-(a,a-dimethylbenzyl)- (6CI,7CI,8CI);2-(4-Hydroxyphenyl)-2-phenylpropane;2-Phenyl-2-(4-hydroxyphenyl)propane;4-(1-Methyl-1-phenylethyl)phenol;4-(Dimethylphenylmethyl)phenol;4-(a,a-Dimethylbenzyl)phenol;4-Cumylphenol;4-Hydroxydiphenyldimethylmethane;NSC 6237;p-(a,a-Dimethylbenzyl)phenol;p-(a-Cumyl)phenol;p-Cumylphenol
• CAS NO: 599-64-4
• Molecular Formula: C₁₅H₁₆O
• Molecular Weight: 212.29
• EINECS: 209-968-0
• Mol File: 599-64-4.mol
• Article Data: 14

Chemical Properties

• Melting Point: 72-75℃
• Boiling Point: 338.5 °C at 760 mmHg
• Flash Point: 160.5 °C
• Appearance: cream solid
• Density: 1.055 g/cm³
• Vapor Pressure: 0.000207mmHg at 25°C
• Refractive Index: 1.587
• CAS DataBase Reference: p-Cumylphenol(CAS DataBase Reference)
• NIST Chemistry Reference: p-Cumylphenol(599-64-4)
• EPA Substance Registry System: p-Cumylphenol(599-64-4)

Safety Data

• Hazard Codes: Xi:Irritant
• Statements: R36/37/38:
• Safety Statements: S26:; S37/39:
• Hazardous Substances Data: 599-64-4(Hazardous Substances Data)

Usage

Description

p-Cumylphenol, also known as 4-Isopropylphenol, is a chemical compound belonging to the phenol group. It is a white solid with a faint odor and is soluble in organic solvents such as ethanol and ether. This versatile compound is widely used as an intermediate in various industries due to its unique properties.

Uses

Used in Plastic and Rubber Industries:
p-Cumylphenol is used as an intermediate for the production of antioxidants, stabilizers, and UV absorbers. Its presence in these additives helps to prevent the degradation of plastics and rubbers, thereby enhancing their durability and performance.
Used in Pharmaceutical Industry:
p-Cumylphenol serves as an intermediate in the production of pharmaceuticals. Its unique chemical structure contributes to the development of various medicinal compounds, making it an essential component in the pharmaceutical manufacturing process.
Used in Disinfectant Production:
Due to its antimicrobial properties, p-Cumylphenol is used as an intermediate in the production of disinfectants. It helps to eliminate harmful microorganisms, ensuring cleanliness and safety in various applications.
Used in Fragrance Industry:
p-Cumylphenol is employed as an intermediate in the production of fragrances. Its unique scent profile contributes to the creation of various fragrances used in personal care and cosmetic products.
Used in Personal Care and Cosmetic Products:
Leveraging its antimicrobial properties, p-Cumylphenol is used in personal care and cosmetic products to maintain cleanliness and prevent the growth of harmful microorganisms. It helps to ensure the safety and efficacy of these products.
However, it is important to note that prolonged or repeated exposure to p-Cumylphenol may cause skin or eye irritation. Therefore, proper safety measures should be taken when handling this compound.

InChI:InChI=1/C15H16O/c1-12(11-13-5-3-2-4-6-13)14-7-9-15(16)10-8-14/h2-10,12,16H,11H2,1H3

Upstream product

• 103-73-1 Phenetole 
• 98-83-9 isopropenylbenzene 
• 52820-06-1 toluene-2,4-di(carbamic acid (4-cumylphenyl) ester) 
• 108-95-2 phenol 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 934-53-2 cumenyl chloride 
• 80-05-7 BPA 
• 98-82-8 Isopropylbenzene 
• 10035-10-6 hydrogen bromide 
• 7446-70-0 aluminium trichloride 
• 617-94-7 1-methyl-1-phenylethyl alcohol 
• 80-15-9 Cumene hydroperoxide 
• 20056-52-4 tri-4-(2-phenylisopropyl)phenyl phosphate 
• 1940-95-0 1-ethoxy-4-(2-phenylpropan-2-yl)benzene 

Downstream Products

• 56949-68-9 1-[4-(1-methyl-1-phenyl-ethyl)-phenoxy]-propan-2-ol 
• 4030-49-3 4-Methoxy-1-(4-α-cumyl-phenoxy)-benzol 
• 98-83-9 isopropenylbenzene 
• 108-95-2 phenol 
• 512799-07-4 4-(4-(1-methyl-1-phenyl-ethyl)-phenoxy)aniline 
• 125023-53-2 6-(p-cumylphenoxy)-1,3-dihydro-1,3-diiminoisoindole 
• 64524-47-6 C₄₆H₄₆O₃ 
• 64523-87-1 C₃₇H₃₆O₃ 
• 64523-66-6 1-Diphenoxymethoxy-4-(1-methyl-1-phenyl-ethyl)-benzene 
• 59427-15-5 Octane-2-sulfonic acid 4-(1-methyl-1-phenyl-ethyl)-phenyl ester 
• 59426-97-0 Butane-2-sulfonic acid 4-(1-methyl-1-phenyl-ethyl)-phenyl ester 
• 6623-93-4 1-(2-(4-methoxyphenyl)propan-2-yl)benzene 
• 91133-59-4 3-methyl-3-phenyl-2-oxobutanoic acid 
• 20056-52-4 tri-4-(2-phenylisopropyl)phenyl phosphate 

Relevant articles and documents

MULTISTEP PROCESS FOR THE PREPARATION OF HEXAMETHYLENE DIISOCYANATE, PENTAMETHYLENE DIISOCYANATE OR TOLUENE DIISOCYANATE

The present invention relates to a multistep process for the preparation of organic diisocyanates by converting the corresponding diamine precursors, urea and hydroxy compounds into monomeric diurethanes, converting these diurethanes into diurethanes of high boiling hydroxy compounds, and finally cleavage of the latter diurethanes to form the diisocyanates and recover the high boiling hydroxy compounds.

METHOD FOR MANUFACTURING α-METHYLSTYRENATED PHENOL

According to an embodiment of the present invention, the present invention provides a method for manufacturing α-methyl styrenated phenol, which comprises the following steps: (a) making phenol react with α-methyl styrene (AMS) under the presence of a first acidic catalyst to obtain a first product; and (b) additionally making 1-5 equivalents of α-methyl styrene for 1 equivalent of phenol react with the first product under the presence of a second acidic catalyst to obtain a second product. The manufactured α-methyl styrenated phenol does not generate environmental damage and is economical.(a) Making phenol react with α-methyl styrene (AMS) under the presence of a first acidic catalyst(AA) Obtaining 30-50 wt% of TMPI, 1-10 wt% DMP, 5-20 wt% of cumyl phenol, 1-10 wt% of AMS trimer, and the remaining phenol(b) Additionally making the α-methyl styrene react with a first product under the presence of a second acidic catalyst(BB) Obtaining 5-50 wt% of TMPI + DMP, 2-20 wt% of cumyl phenol, 1-10 wt% of dicumene, 20-60 wt% of dicumyl phenol, and 0.1-5 wt% of AMS trimerCOPYRIGHT KIPO 2017

Calcium-catalyzed hydroarylation of alkenes at room temperature

Calcium-catalyst gaining ground: A variety of electron-poor electron-rich and trisubstituted styrene derivatives were reacted to give the desired diarylalkanes within less than an hour at room temperature in the presence of 2.5 mol % of Ca(NTf2)2/Bu4NPF6 (see scheme). Additionally the highly reactive calcium catalyst was successfully applied for the hydroarylation of dienes and even trisubstituted olefins.