598-99-2 Usage
Description
Methyl trichloroacetate is a colorless, clear liquid that is denser than water and insoluble in water. It has the potential to slightly irritate skin, eyes, and mucous membranes, and may be toxic if ingested. This chemical is primarily used in the production of other chemicals.
Uses
Used in Chemical Synthesis:
Methyl trichloroacetate is used as an intermediate chemical for the synthesis of various other chemicals, contributing to the development and production of a range of compounds in the chemical industry.
Used in Protein Studies:
In the field of biochemistry, Methyl trichloroacetate is utilized as a negative staining agent for proteins. This application allows for the visualization of protein structures under a microscope, which is crucial for biological studies and research. Additionally, it enables the recovery of unmodified proteins for further analysis or transblot for amino acid sequence determination, facilitating a deeper understanding of protein functions and interactions.
Reactions
methyl trichloroacetate reacts with sodium methoxide then the formed product is carbine.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
A halogenated ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides. A mixture of the ester and trimethylamine reacted violently. Polymerization of a reactive dehydrochlorination of the ester was viewed as the most likely product, along with generous amounts of heat.
Health Hazard
TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Contact with molten substance may cause severe burns to skin and eyes. Reaction with water or moist air will release toxic, corrosive or flammable gases. Reaction with water may generate much heat that will increase the concentration of fumes in the air. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.
Fire Hazard
Combustible material: may burn but does not ignite readily. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water.
Check Digit Verification of cas no
The CAS Registry Mumber 598-99-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,9 and 8 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 598-99:
(5*5)+(4*9)+(3*8)+(2*9)+(1*9)=112
112 % 10 = 2
So 598-99-2 is a valid CAS Registry Number.
InChI:InChI=1/C3H3Cl3O2/c1-8-2(7)3(4,5)6/h1H3
598-99-2Relevant articles and documents
Determination of hexachloroacetone in air.
Kissa
, p. 1222 - 1225 (1983)
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Electrocarboxylation of CCI4 in MeCN during electrolysis with the sacrificial Zn anode
Sigacheva,Neverov,Petrosyan
experimental part, p. 297 - 302 (2010/07/09)
The regularities of galvanostatic electrocarboxylation of CCl4 in Alk4NBr/MeCN in an undivided cell with sacrificial Zn anode were studied. The major product of the electrolysis is zinc trichloroacetate, which is formed as a result o
Reactions of trialkyl phosphites with mono- and diacylals of halo-substituted acetic acids
Gazizov,Gaisin,Khairullin,Safina,Karimova,Petrova
, p. 1738 - 1741 (2007/10/03)
Trialkyl phosphites react with diacylals of di- and trichloroacetic acids by the pathway of the Perkow reaction; with monoacylals of bromo- and iodoacetic acids, by the pathway of the classical Arbuzov reaction; and with monoacylals of di- and trichloroacetic acids, by the pathway of the nonclassical Arbuzov reaction.
