5955-73-7

Basic information

• Product Name: 2-METHYLBENZOYL CYANIDE
• Synonyms: 2-METHYLBENZOYL CYANIDE;OXO-O-TOLYL-ACETONITRILE;2-methyl phenyl glyoxylonitrile;Benzeneacetonitrile, 2-Methyl-a-oxo-
• CAS NO: 5955-73-7
• Molecular Formula: C₉H₇NO
• Molecular Weight: 145.16
• EINECS: 200-258-5
• Mol File: 5955-73-7.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 239.226 °C at 760 mmHg
• Flash Point: 98.481 °C
• Appearance: /
• Density: 1.111 g/cm³
• Vapor Pressure: 0.041mmHg at 25°C
• Refractive Index: 1.541
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-METHYLBENZOYL CYANIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYLBENZOYL CYANIDE(5955-73-7)
• EPA Substance Registry System: 2-METHYLBENZOYL CYANIDE(5955-73-7)

Safety Data

• Hazardous Substances Data: 5955-73-7(Hazardous Substances Data)

Usage

Chemical Properties

Colorless liquid

InChI:InChI=1/C9H7NO/c1-7-4-2-3-5-8(7)9(11)6-10/h2-5H,1H3

Upstream product

• 592-04-1 mercury(II) cyanide 
• 933-88-0 ortho-toluoyl chloride 
• 22364-68-7 2-tolylmethylnitrile 
• 84452-03-9 Dichloro-o-tolyl-acetonitrile 
• 85589-34-0 2-hydroxy-2-(2-methylphenyl)acetonitrile 
• 74-90-8 hydrogen cyanide 
• 773837-37-9 sodium cyanide 
• 118-90-1 ortho-methylbenzoic acid 
• 143-33-9 sodium cyanide 
• 1052175-57-1 C₉H₈BrN 
• 529-20-4 2-methylphenyl aldehyde 
• 151-50-8 potassium cyanide 
• 82128-96-9 2-trimethylsilyloxy-2-(2-methylphenyl)acetonitrile 
• 7677-24-9 trimethylsilyl cyanide 

Downstream Products

• 89-71-4 2-Methyl-benzoic acid methyl ester 
• 34966-54-6 methyl 2-oxo-2-(o-tolyl)acetate 
• 6566-40-1 4-oxo-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid 
• 1265379-64-3 C₁₇H₁₅NO₃ 
• 1255526-44-3 C₁₇H₁₅NO₃ 
• 133409-72-0 methyl (E)-2-[2-(bromomethyl)phenyl]-2-(methoxyimino)acetate 
• 120974-97-2 methyl-(E)-2-(2-tolyl)-2-methoxyiminoacetate 
• 144106-03-6 (Z)-2-(2-tolyl)-2-methoxyiminoacetic acid methyl ester 

Relevant articles and documents

Preparation method of O-methylbenzoyl nitrile

The method comprises the following steps: firstly dissolving o-methylbenzoic acid in a toluene solvent, dropping the dimethyl sulfoxide to carry out reaction, and removing a small amount of unreacted dichlorosulphoxide at low temperature after the reactio

Acceptorless and Base-free Dehydrogenation of Cyanohydrin with (η6-Arene)halide(Bidentate Phosphine)ruthenium(II) Complex

Ruthenium-catalyzed dehydrogenation of cyanohydrins under acceptorless and base-free conditions was demonstrated for the first time in the synthesis of acyl cyanide. As opposed to the thermodynamically preferred elimination of hydrogen cyanide, the dehydrogenation of cyanohydrins could be kinetically controlled with ruthenium (II) bidentate phosphine complexes. The effects of the arene, phosphine ligands and counter anions were investigated in regard to catalytic activity and selectivity. Selective dehydrogenation can occur via β-hydride elimination with the experimentally observed [(alkoxide)Ru] complex. (Figure presented.).

A stretching of the intermediate O-methyl benzoyl nitrile synthetic method

The invention relates to a method for preparing a key intermediate methylbenzoyl cyanide in the process of synthesizing trifloxystrobin. The method comprises the following steps: adding o-toluoyl chloride, a solvent and a catalyst into a reaction kettle; introducing metered hydrocyanic acid gas, completely reacting under a heat insulating conditon to obtain methylbenzoyl cyanide, and carrying out back-distillation to obtain a methylbenzoyl cyanide product. The content of methylbenzoyl cyanide is over 99 percent and the yield can be over 95 percent metered in form of o-toluoyl chloride. The method is simple and convenient to operate, the utilization of the raw material o-toluoyl chloride is high; except the byproduct hydrochloric acid, almost no other wastes are generated, and atomic economic reaction is basically realized. The method is a synthesizing process with good economic prospect.