5943-34-0

Basic information

• Product Name: DIISOPROPYL TRISULFIDE
• Synonyms: FEMA 3968;DIISOPROPYL TRISULFIDE;diisopropyl trisulphide;2-PROPAN-2-YLSULFANYLDISULFANYLPROPANE;Bis(1-methylethyl) pertrisulfide;Diisopropyl pertrisulfide;Einecs 227-703-7;Trisulfide,bis(1-methylethyl)
• CAS NO: 5943-34-0
• Molecular Formula: C₆H₁₄S₃
• Molecular Weight: 182.37
• EINECS: 227-703-7
• Product Categories: sulfide Flavor
• Mol File: 5943-34-0.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 79°C/6.5mmHg(lit.)
• Flash Point: 96 °C
• Appearance: /
• Density: 1.071 g/cm³
• Vapor Pressure: 0.0495mmHg at 25°C
• Refractive Index: 1.5360-1.5400
• CAS DataBase Reference: DIISOPROPYL TRISULFIDE(CAS DataBase Reference)
• NIST Chemistry Reference: DIISOPROPYL TRISULFIDE(5943-34-0)
• EPA Substance Registry System: DIISOPROPYL TRISULFIDE(5943-34-0)

Safety Data

• Hazardous Substances Data: 5943-34-0(Hazardous Substances Data)

Usage

Uses

Used in Flavor and Fragrance Industry:
DIISOPROPYL TRISULFIDE is used as a flavoring agent for its characteristic garlic-like aroma, adding a unique taste and scent to various food products and beverages.
Used in Pharmaceutical Industry:
DIISOPROPYL TRISULFIDE is used as a pharmaceutical intermediate for the synthesis of various drugs and medications, leveraging its chemical properties to create effective treatments.
Used in Chemical Research:
DIISOPROPYL TRISULFIDE serves as a valuable compound in chemical research, providing insights into the behavior and reactions of sulfur-containing organic compounds, contributing to the development of new materials and technologies.

InChI:InChI=1/C6H14S3/c1-5(2)7-9-8-6(3)4/h5-6H,1-4H3

Upstream product

• 75-26-3 isopropyl bromide 
• 7783-06-4 hydrogen sulfide 
• 67-64-1 acetone 
• 19760-04-4 isopropylsulfenyl chloride 
• 29684-56-8 Burgess Reagent 
• 75-33-2 2-propanethiol 
• 67692-55-1 isopropylthiosulfenyl chloride 
• 18156-74-6 1-(Trimethylsilyl)imidazole 
• 13686-82-3 dithiosulfurous acid S,S'-diisopropyl ester 
• 61775-32-4 (disulfido)carbonic acid SS-isopropyl ester O-methyl ester 

Relevant articles and documents

A rapid, efficient and green procedure for transformation of alkyl halides/ tosylates to organochalcogens in water

A one-pot and efficient synthesis of dialkyl dichalcogenides (S, Se) in aqueous media under catalyst-free conditions using benzylic, allylic and primary halides with elemental sulfur and selenium has been developed. Also, this procedure was extended to preparation of trisulfides and triselenides from secondary and tertiary halides in same condition. In all cases, products can be obtained in good to excellent yield in short reactions time.

Simple and green method for synthesis of symmetrical dialkyl disulfides and trisulfides from alkyl halides in water; PMOxT as a sulfur donor

An environmentally new, mild and efficient method has been developed for the synthesis of dialkyl disulfides and dialkyl trisulfides in aqueous conditions by a reaction between alkyl halides (and tosylate) and potassium-5-methyl-1,3,4-oxadiazole-2-thiolate (PMOxT) as a sulfur transfer reagent. The advantages of this method are that it occurs under mild reaction conditions, it is base free, it uses water as the solvent and it occurs in high yields. A variety of dialkyl disulfides and dialkyl trisulfides can be obtained in good to excellent yields up to 98%.

Unexpected reactivity of the Burgess reagent with thiols: Synthesis of symmetrical disulfides

(Equation Presented) Reaction of the Burgess reagent with a series of aliphatic and aromatic thiols led to the corresponding symmetrical disulfides in high yields. No olefins were detected in the reactions of aliphatic thiols.

Use of a sacriflcial-sulfur electrode in electroorganic chemistry. V. Formation of the sequence CSSSC from S and thiols or thiolates

At a working potential of about +2.0 V (vs SCE) the carbon-sulfur electrode is a source of the electrogenerated cation S2+. In organic media, this electrophile reacts with thiols (or thiolates) to give a mixture of polysulfides of which the trisulfide is the main product. The reaction between electrogenerated Sy2- and alkyl halides is less selective. Elsevier,.

A simple method to prepare unsymmetrical di- tri- and tetrasulfides

Unsymmetrical di- tri- and tetrasulfides can be prepared in a one-pot reaction using SO2Cl2 SCl2 and S2Cl2 respectively to permit coupling of the appropriate thiols.

REACTION OF SULFUR DIOXIDE WITH THIOLS CATALYZED BY BORON TRIFLUORIDE ETHERATE. EVIDENCE FOR A POSSIBLE INTERVENTION OF DITHIOSULFITE AS A REACTION INTERMEDIATE.

The reaction of sulfur dioxide (SO//2) with 1-propanethiol (NPT), 2-propanethiol (IPT), or 2-methyl-2-propanethiol (TBT) catalyzed by boron trifluoride ethrate (BF//3OEt//2) was investigated. The ratios of dialkyl trisulfide to dialkyl disulfide obtained (RSSSR/RSSR) at an early stage of the reaction were larger than 1 for the reaction of TBT and less than 1 for the reaction of NPT or IPT. The reaction of dithiosulfites with BF//3OEt//2 in the presence or absence of thiol was investigated. From a consideration of the similarity of the composition of the sulfides formed in the reaction of dithiosulfites with BF//3OEt//2 to those in the reaction of SO//2 witn thiol in the presence of BF//3OEt//2, the possibility of the intervention of dithiosulfite as a reaction intermediate in the reaction of SO//2 with thiol is discussed.

A NEW SYNTHESIS OF ORGANIC TRISULFIDES

Thiols react with diimidazolylsulfide under mild conditions to give simmetrical trisulfides in good yield and high purity.