58949-77-2

Basic information

• Product Name: Benzonitrile, 4,4'-(3-oxo-1-propene-1,3-diyl)bis-
• CAS NO: 58949-77-2
• Molecular Formula: C17H10N2O
• Molecular Weight: 258.279
• Mol File: 58949-77-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzonitrile, 4,4'-(3-oxo-1-propene-1,3-diyl)bis-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 4,4'-(3-oxo-1-propene-1,3-diyl)bis-(58949-77-2)
• EPA Substance Registry System: Benzonitrile, 4,4'-(3-oxo-1-propene-1,3-diyl)bis-(58949-77-2)

Safety Data

• Hazardous Substances Data: 58949-77-2(Hazardous Substances Data)

Upstream product

• 1443-80-7 4-cyanophenyl methyl ketone 
• 105-07-7 4-cyanobenzaldehyde 
• 58949-72-7 C₁₇H₁₂N₂O₂ 
• 874-89-5 4-Cyanobenzyl alcohol 
• 874-86-2 4-cyanobenzyl chloride 

Downstream Products

• 62584-98-9 1,3-Bis(4-cyanophenyl)-1-propanone 
• 61625-49-8 1,3-Bis-(4-amidinophenyl)-1-propanone 
• 229308-73-0 1,3-bis(4-cyanophenyl)-2,3-dibromopropan-1-one 
• 55368-75-7 1,3-bis(4-cyanophenyl)isoxazole 
• 229308-74-1 2,4-bis(4-cyanophenyl)furan 
• 195718-80-0 methyl 3-(4-cyanophenyl)-5-(4-cyanophenyl)pentanoate 
• 55368-72-4 4,4'-(1H-pyrazole-3,5-diyl)dibenzonitrile 

Relevant articles and documents

Biosynthesis of ZrO2 for ZrO2@Ag-S-CH2COOH as the retrievable catalyst for the one-pot green synthesis of pyrazoline derivatives and their anticancer evaluation

In the present work, Ficus benghalensis leaf extract was used for the synthesis of ZrO2 nanoparticles. Further, ZrO2@Ag-S-CH2-COOH was synthesized using biosynthesized ZrO2, and its catalytic potential was examined in the synthesis of pyrazoline from reaction of chalcone and hydrazine hydrate at room temperature. The structural conformation of ZrO2@Ag-S-CH2-COOH has been done using FT-IR, SEM, EDX, XRD, TGA-TDA, XPS, and DLS techniques, high turnover number (TON), and high turnover frequency. The ZrO2@Ag-S-CH2-COOH demonstrated outstanding catalytic activity for the synthesis of pyrazolines. The structures of the pyrazoline derivatives were confirmed by FT-IR, 1H and 13C NMR, and mass spectrometry techniques. Synthesized pyrazoline were tested for anticancer activity against human lung cancer cell line A549 study and confirmed by molecular docking investigations.

2,4-Diphenyl furan diamidines as novel anti-Pneumocystis carinii pneumonia agents

Dicationic 2,4-bis(4-amidinophenyl)furans 5-10 and 2,4-bis(4- amidinophenyl)-3,5-dimethylfurans 14 and 15 have been synthesized. Thermal melting studies revealed high binding affinity of the compounds to poly(dA- dT) and to the duplex oligomer d(CGCGAATTC

Rational design and synthesis of novel, potent bis-phenylamidine carboxylate factor Xa inhibitors

The molecular modeling studies, rational design, and synthesis of a novel series of bis-phenylamidine carboxylate compounds which are inhibitors of factor Xa in the blood coagulation cascade are described. Inhibition of blood coagulation has been proposed