57469-76-8

Basic information

• Product Name: Ibuprofen lysinate
• Synonyms: 2-(4-Isobutylphenyl)propionic acid lysinate;Ibuprofen lysinate
• CAS NO: 57469-76-8
• Molecular Formula: C₆H₁₄N₂O₂*C₁₃H₁₈O₂
• Molecular Weight: 352.47
• Mol File: 57469-76-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 549.7 °C at 760 mmHg
• Flash Point: 286.2 °C
• Appearance: /
• Vapor Pressure: 6.47E-13mmHg at 25°C
• Storage Temp.: Refrigerator
• Solubility: Methanol (Slightly), Water (Slightly)
• CAS DataBase Reference: Ibuprofen lysinate(CAS DataBase Reference)
• NIST Chemistry Reference: Ibuprofen lysinate(57469-76-8)
• EPA Substance Registry System: Ibuprofen lysinate(57469-76-8)

Safety Data

• Hazardous Substances Data: 57469-76-8(Hazardous Substances Data)

Usage

Description

Ibuprofen lysinate is a water-soluble form of the nonsteroidal anti-inflammatory drug (NSAID) Ibuprofen. It is designed to enhance the absorption rate of the drug, making it more effective for rapid relief. Ibuprofen lysinate possesses anti-inflammatory, analgesic, and antipyretic properties, which contribute to its wide range of applications in various industries.

Uses

Used in Pharmaceutical Industry:
Ibuprofen lysinate is used as an active pharmaceutical ingredient for the treatment of various types of pain, including headaches, muscle aches, menstrual cramps, and dental pain. Its rapid absorption allows for quicker relief compared to other forms of Ibuprofen.
Used in Sports Medicine:
Ibuprofen lysinate is used as an anti-inflammatory agent to help reduce inflammation and pain associated with sports injuries. Its fast-acting properties make it a popular choice for athletes seeking immediate relief from minor injuries and overexertion.
Used in Pain Management:
Ibuprofen lysinate is used as a pain management tool for patients experiencing mild to moderate pain from various conditions, such as arthritis, tendinitis, and other musculoskeletal disorders. Its rapid absorption allows for a quicker onset of pain relief, improving the patient's quality of life.
Used in Veterinary Medicine:
Ibuprofen lysinate is also used in veterinary medicine as an anti-inflammatory and analgesic agent for the treatment of pain and inflammation in animals. Its water-soluble form makes it easier to administer and absorb, providing faster relief for pets suffering from various conditions.

InChI:InChI=1/C13H18O2.C6H14N2O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15;7-4-2-1-3-5(8)6(9)10/h4-7,9-10H,8H2,1-3H3,(H,14,15);5H,1-4,7-8H2,(H,9,10)/p-1

Synthetic route

2,6-diaminocaproic acid (70-54-2, 923-27-3, 6899-06-5, 60103-30-2, 60132-27-6, 56-87-1) + ibuprofen (15687-27-1) → lysine p-isobutylphenylpropionate (57469-76-8)

Conditions	Yield
In ethanol at 25℃; for 0.166667h; Temperature;

Upstream product

• 70-54-2 2,6-diaminocaproic acid 
• 15687-27-1 ibuprofen 

Relevant articles and documents

Preparation method of lysinoprofen

The invention belongs to the technical field of medicine preparation, and particularly relates to a preparation method of lysinoprofen. The preparation method comprises the following steps: concentrating lysine hydrochloride and then reacting lysine hydrochloride with ibuprofen, and decolorizing with activated carbon, and crystallizing with ethyl acetate to obtain the product. The method for preparing lysinoprofen is simple, does not need special equipment, and is simple and convenient to operate and good in process controllability; and the prepared finished product is good in quality and highin purity.