5627-39-4Relevant articles and documents
ortho-halogen naphthaleins as specific inhibitors of Lactobacillus casei thymidylate synthase. Conformational properties and biological activity
Ghelli, Stefano,Rinaldi, Marcella,Barlocco, Daniela,Gelain, Arianna,Pecorari, Piergiorgio,Tondi, Donatella,Rastelli, Giulio,Costi, Maria Paola
, p. 951 - 963 (2007/10/03)
Thymidylate synthase (TS) (EC 2.1.1.45), an enzyme involved in the DNA synthesis of both prokaryotic and eukaryotic cells, is a potential target for the development of anticancer and antinfective agents. Recently, we described a series of phthalein and na