56138-96-6Relevant articles and documents
Highly Robust Palladium(II) α-Diimine Catalysts for Slow-Chain-Walking Polymerization of Ethylene and Copolymerization with Methyl Acrylate
Dai, Shengyu,Sui, Xuelin,Chen, Changle
, p. 9948 - 9953 (2015)
A series of sterically demanding α-diimine ligands bearing electron-donating and electron-withdrawing substituents were synthesized by an improved synthetic procedure in high yield. Subsequently, the corresponding Pd complexes were prepared and isolated by column chromatography. These Pd complexes demonstrated unique properties in ethylene polymerization, including high thermal stability and high activity, thus generating polyethylene with a high molecular weight and very low branching density. Similar properties were observed for ethylene/methyl acrylate copolymerization. Because of the high molecular weight and low branching density, the generated polyethylene and ethylene/methyl acrylate copolymer were semicrystalline solids. The (co)polymers had unique microstructures originating from the unique slow-chain-walking activity of these Pd complexes.
Aluminum Amidinates: Insights into Alkyne Hydroboration
Hobson, Katie,Carmalt, Claire J.,Bakewell, Clare
supporting information, p. 10958 - 10969 (2021/08/03)
The mechanism of the aluminum-mediated hydroboration of terminal alkynes was investigated using a series of novel aluminum amidinate hydride and alkyl complexes bearing symmetric and asymmetric ligands. The new aluminum complexes were fully characterized and found to facilitate the formation of the (E)-vinylboronate hydroboration product, with rates and orders of reaction linked to complex size and stability. Kinetic analysis and stoichiometric reactions were used to elucidate the mechanism, which we propose to proceed via the initial formation of an Al-borane adduct. Additionally, the most unstable complex was found to promote decomposition of the pinacolborane substrate to borane (BH3), which can then proceed to catalyze the reaction. This mechanism is in contrast to previously reported aluminum hydride-catalyzed hydroboration reactions, which are proposed to proceed via the initial formation of an aluminum acetylide, or by hydroalumination to form a vinylboronate ester as the first step in the catalytic cycle.
Solving the challenging synthesis of highly cytotoxic silver complexes bearing sterically hindered NHC ligands with mechanochemistry
Bantreil, Xavier,Beillard, Audrey,Gaillard, Sylvain,Gatignol, Jérémie,Lamaty, Frédéric,Métro, Thomas-Xavier,Quintin, Fran?ois,Renaud, Jean-Luc,Retailleau, Pascal
supporting information, p. 12592 - 12598 (2020/10/02)
The use of ball-mills enabled the straightforward synthesis of a variety of silver(i) complexes featuring challenging NHC ligands. Sterically hindered including electron-poor or with very low solubility imidazolium salts were ground with silver(i) oxide to furnish heteroleptic or homoleptic complexes in high yields and short reaction times. The synthesis of heteroleptic bis-NHC silver(i) complexes was also performed for the first time in a ball mill. The efficiency and rapidity of the mechanochemical approach enabled the generation of a library of unprecedented NHC silver complexes, whose cytotoxicity on the HCT116 colorectal cancer cell line was evaluated providing a rare example of medicinal mechanochemistry. The cationic silver complexes were found to be more potent than the neutral analogues, with IC50values down to 21 nM and 256 times more potent than cisplatin.
