56107-02-9 Usage
Description
4-Chloro-3-nitrobenzophenone, also known as (4-Chloro-3-nitrophenyl)phenyl-methanone, is a pale yellow crystalline powder that serves as a valuable starting material for organic synthesis. It is a derivative of benzophenone, featuring a chlorine atom at the 4-position and a nitro group at the 3-position, which imparts unique chemical properties to the molecule.
Uses
Used in Organic Synthesis:
4-Chloro-3-nitrobenzophenone is used as a starting material for the synthesis of various organic compounds. Its unique structural features, including the chlorine and nitro groups, make it a versatile building block for creating a wide range of molecules with different functional groups and applications across various industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-Chloro-3-nitrobenzophenone is used as an intermediate for the synthesis of various drugs and drug candidates. Its chemical properties allow for the development of molecules with potential therapeutic applications, such as antimicrobial, anti-inflammatory, and anticancer agents.
Used in Chemical Research:
4-Chloro-3-nitrobenzophenone is also utilized in chemical research for studying reaction mechanisms, exploring new synthetic routes, and developing novel methodologies in organic chemistry. Its reactivity and structural features make it an interesting subject for academic and industrial research.
Used in Dye and Pigment Industry:
In the dye and pigment industry, 4-Chloro-3-nitrobenzophenone can be used as a precursor for the synthesis of various dyes and pigments with specific color properties. Its unique structure allows for the development of new colorants with improved performance characteristics, such as enhanced color strength, lightfastness, and stability.
Used in Material Science:
4-Chloro-3-nitrobenzophenone can be employed in the development of new materials with specific properties, such as photoactive materials, sensors, and advanced polymers. Its chemical properties can be exploited to create materials with unique optical, electronic, or mechanical characteristics for various applications in the material science field.
Check Digit Verification of cas no
The CAS Registry Mumber 56107-02-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,1,0 and 7 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 56107-02:
(7*5)+(6*6)+(5*1)+(4*0)+(3*7)+(2*0)+(1*2)=99
99 % 10 = 9
So 56107-02-9 is a valid CAS Registry Number.
InChI:InChI=1/C13H8ClNO3/c14-11-7-6-10(8-12(11)15(17)18)13(16)9-4-2-1-3-5-9/h1-8H
56107-02-9Relevant articles and documents
Chemoselective Synthesis of Aryl Ketones from Amides and Grignard Reagents via C(O)-N Bond Cleavage under Catalyst-Free Conditions
Sureshbabu, Popuri,Azeez, Sadaf,Muniyappan, Nalluchamy,Sabiah, Shahulhameed,Kandasamy, Jeyakumar
, p. 11823 - 11838 (2019/10/02)
Conversion of a wide range of N-Boc amides to aryl ketones was achieved with Grignard reagents via chemoselective C(O)-N bond cleavage. The reactions proceeded under catalyst-free conditions with different aryl, alkyl, and alkynyl Grignard reagents. α-Ketoamide was successfully converted to aryl diketones, while α,β-unsaturated amide underwent 1,4-addition followed by C(O)-N bond cleavage to provide diaryl propiophenones. N-Boc amides displayed higher reactivity than Weinreb amides with Grignard reagents. A broad substrate scope, excellent yields, and quick conversion are important features of this methodology.
MEBENDAZOLE POLYMORPH FOR TREATMENT AND PREVENTION OF TUMORS
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, (2016/09/22)
Mebendazole is an antiparasitic drug with over 40 years of safe use. Recently mebendazole was repurposed for glioblastoma therapy. Three polymorphs of mebendazole exist, but the relative polymorph content for existing drugs varies, and the therapeutic anti-cancer relevance of the different polymorphs was unknown. As an oral drug mebendazole polymorph C is a superior form, and it reaches the brain and brain tumors in effective concentrations. Efficacy is further improved by combining mebendazole with a P-glycoprotein inhibitor. Mebendazole may also be used for therapy of other cancers, as well as a chemo-preventative agent.
