5470-17-7

Basic information

• Product Name: 2-Chloro-3-bromo-5-nitropyridine
• Synonyms: 3-BROMO-2-CHLORO-5-NITROPYRIDINE;2-CHLORO-3-BROMO-5-NITROPYRIDINE;3-Bromo-2-chloro-5-nitropyridine 98%;NSC 26278;2 - chloro - 3 - broMine - 5 - nitro pyridine
• CAS NO: 5470-17-7
• Molecular Formula: C₅H₂BrClN₂O₂
• Molecular Weight: 237.44
• Product Categories: blocks;Bromides;NitroCompounds;Pyridines;Pyridine;Pyridine series;Boronic Acid;Heterocycle-Pyridine series
• Mol File: 5470-17-7.mol
• Article Data: 7

Chemical Properties

• Melting Point: 54-58
• Boiling Point: 293.835 °C at 760 mmHg
• Flash Point: 131.507 °C
• Appearance: /
• Density: 1.936 g/cm³
• Vapor Pressure: 0.00295mmHg at 25°C
• Refractive Index: 1.627
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: -4.99±0.10(Predicted)
• CAS DataBase Reference: 2-Chloro-3-bromo-5-nitropyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-3-bromo-5-nitropyridine(5470-17-7)
• EPA Substance Registry System: 2-Chloro-3-bromo-5-nitropyridine(5470-17-7)

Safety Data

• Hazard Codes: Xi,T
• Statements: 25-41
• Safety Statements: 26-39-45
• RIDADR: 2811
• WGK Germany: 1
• HazardClass: IRRITANT
• PackingGroup: Ⅲ
• Hazardous Substances Data: 5470-17-7(Hazardous Substances Data)

Usage

Description

2-Chloro-3-bromo-5-nitropyridine is a halogenated nitropyridine derivative with the molecular formula C5H2BrClN2O2. It is a yellow crystalline powder that is widely used in the synthesis of pharmaceuticals and agrochemicals. 2-Chloro-3-bromo-5-nitropyridine is known for its ability to undergo various chemical reactions, making it a versatile building block in organic synthesis. Its potential applications in the development of antineoplastic and antitumor agents, as well as in the production of herbicides and insecticides, make it of interest to researchers and manufacturers in the fields of pharmaceuticals and agrochemicals.

Uses

Used in Pharmaceutical Industry:
2-Chloro-3-bromo-5-nitropyridine is used as an intermediate in the synthesis of antineoplastic and antitumor agents. Its unique chemical structure allows for the development of various compounds with potential therapeutic effects against cancer.
Used in Agrochemical Industry:
2-Chloro-3-bromo-5-nitropyridine is used as a building block in the production of herbicides and insecticides. Its versatility in chemical reactions enables the creation of effective compounds for controlling pests and unwanted plant growth in agricultural settings.
Used in Organic Synthesis:
2-Chloro-3-bromo-5-nitropyridine is used as a versatile building block in organic synthesis. Its ability to undergo various chemical reactions makes it a valuable component in the development of new compounds for a wide range of applications, including pharmaceuticals, agrochemicals, and other industries.

InChI:InChI=1/C5H2BrClN2O2/c6-4-1-3(9(10)11)2-8-5(4)7/h1-2H

Upstream product

• 5418-51-9 5-nitro-2-hydroxypyridine 
• 15862-33-6 3-bromo-2-hydroxy-5-nitropyridine 

Downstream Products

• 186593-42-0 3-bromo-2-methyl-5-nitropyridine 
• 16098-21-8 3-bromo-1-methyl-5-nitropyridin-2(1H)-one 
• 15862-50-7 3-bromo-2-methoxy-5-nitropyridine 
• 353285-86-6 4-(3-methyl-5-nitropyridin-2-yl)morpholine 
• 1428799-39-6 C₁₁H₈BrN₃O₂ 
• 209328-99-4 5-bromo-6-fluoropyridin-3-amine 
• 186593-43-1 5-amino-3-bromo-2-methylpyridine 
• 1445993-04-3 N-[5-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)-6-phenoxypyridin-3-yl]methanesulfonamide 
• 1445994-19-3 4-(5-amino-2-phenoxypyridin-3-yl)-6-methyl-1-tosyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one 
• 1445994-18-2 6-methyl-4-(5-nitro-2-phenoxypyridin-3-yl)-1-tosyl-1H-pyrrolo[2,3-c]pyridin-7(6H)-one 

Relevant articles and documents

A 2-amino-thiazole compounds (by machine translation)

The present invention relates to the technical field of pharmaceutical chemistry, particularly relates to a 2-amino thiazole compound or its pharmaceutically acceptable salts, its preparation method, and pharmaceutical compositions containing such compounds and its application in the preparation of antineoplastic. (by machine translation)

Amino substituted aryloxybenzylpiperidine derivatives

This invention is directed to Amino substituted Aryloxybenzylpiperidine derivatives which are ligands at the MCH1 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by admixing a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject an amount of a compound of the subject invention. This invention also provides a method of treating a subject suffering from obesity which comprises administering to the subject an amount of a compound of the subject invention.

Amino substituted aryloxybenzylpiperidine derivatives

This invention is directed to Amino substituted Aryloxybenzylpiperidine derivatives which are ligands at the MCH1 receptor. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a pharmaceutical composition made by admixing a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject a therapeutically effective amount of a compound of the subject invention. This invention also provides a method of treating a subject suffering from obesity which comprises administering to the subject a therapeutically effective amount of a compound of the subject invention.