5463-11-6

Basic information

• Product Name: [bis(4-chlorophenyl)methylidene]hydrazine
• CAS NO: 5463-11-6
• Molecular Formula: C₁₃H₁₀Cl₂N₂
• Molecular Weight: 265.1379
• Mol File: 5463-11-6.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 378.1°C at 760 mmHg
• Flash Point: 182.5°C
• Density: 1.29g/cm³
• Vapor Pressure: 6.43E-06mmHg at 25°C
• Refractive Index: 1.614
• CAS DataBase Reference: [bis(4-chlorophenyl)methylidene]hydrazine(CAS DataBase Reference)
• NIST Chemistry Reference: [bis(4-chlorophenyl)methylidene]hydrazine(5463-11-6)
• EPA Substance Registry System: [bis(4-chlorophenyl)methylidene]hydrazine(5463-11-6)

Safety Data

• Hazardous Substances Data: 5463-11-6(Hazardous Substances Data)

Usage

Description

[bis(4-chlorophenyl)methylidene]hydrazine, also known as a hydrazine derivative, is a chemical compound with the molecular formula C14H14Cl2N2. It features two 4-chlorophenyl groups attached to a central methylene group, which is further linked to a hydrazine moiety. [bis(4-chlorophenyl)methylidene]hydrazine is known for its unique structural properties and potential applications in various fields.

Uses

Used in Organic Synthesis:
[bis(4-chlorophenyl)methylidene]hydrazine is utilized as a key intermediate in the synthesis of various organic compounds. Its unique structure allows for the creation of a wide range of chemical products, making it a valuable component in organic chemistry.
Used in Chemical Reactions as a Reagent:
[bis(4-chlorophenyl)methylidene]hydrazine also serves as a reagent in numerous chemical reactions, facilitating the formation of desired products and aiding in the advancement of chemical research and development.
Used in Pharmaceutical Research:
Due to its distinctive structural properties, [bis(4-chlorophenyl)methylidene]hydrazine may have potential applications in pharmaceutical research. Its ability to form various organic compounds and participate in chemical reactions could contribute to the discovery and development of new pharmaceutical agents.
It is crucial to handle [bis(4-chlorophenyl)methylidene]hydrazine with care, as it can be hazardous if not used properly. Proper safety measures and precautions should be taken to ensure the safe use of this compound in any application.

Upstream product

• 90-98-2 4,4'-Dichlorobenzophenone 

Downstream Products

• 101-76-8 4,4'-dichlorodiphenylmethane 
• 1143-92-6 bis-(4-chlorophenyl)diazomethane 
• 50482-89-8 tetrakis(p-chlorophenyl)diazine 
• 1540-63-2 4,4'-(2,2-difluoroethene-1,1-diyl)bis(chlorobenzene) 
• 57070-99-2 4,4'-dichlorobenzhydryl ethyl ether 
• 13271-47-1 -p-dimethylaminophenyl-diphenyl-phosphazin 
• 13271-46-0 -triphenylphosphazin 
• 79289-41-1 1-(4,4'-dichlorodiphenylmethylene)-3-oxo-1,2-diazetidinium hydroxide, inner salt 
• 106864-92-0 benzyl bis(4-chlorophenyl)methanethiosulfonate 
• 106864-84-0 methyl bis(4-chlorophenyl)methanesulfinate 
• 78525-36-7 1,1,2,2-tetrakis(4-chlorophenyl)ethene 
• 86456-49-7 Methyl 1-methyl-2,2-bis(4-chlorophenyl)cyclopropanecarboxylate 

Relevant articles and documents

Copper-Mediated Cross-Coupling of Diazo Compounds with Sulfinates

A copper-mediated cross-coupling reaction between a diazo compound and a sodium alkane(arene)sulfinate gives a sulfone as the product. This reaction proceeds under mild conditions and features excellent functional group compatibility. A wide range of sodium alkane(arene)sulfinates were successfully applied in this chemistry. Mechanistic studies revealed that the overall reaction efficiency of the sulfinates was in line with their nucleophilicity in this reaction.

Direct α-Monofluoroalkenylation of Heteroatomic Alkanes via a Combination of Photoredox Catalysis and Hydrogen-Atom-Transfer Catalysis

In this study, a new C(sp3)-H monofluoroalkenylation reaction involving cooperative visible-light photoredox catalysis and hydrogen-atom-transfer catalysis to afford products generated by selective hydrogen abstraction and radical-radical cross-coupling was described. This mild, efficient reaction shows high regioselectivity for the α-carbon atoms of amines, ethers, and thioethers and thus allows the preparation of monofluoroalkenes bearing various substituents. The reaction was applied to two bioactive molecules, indicating its utility for late-stage monofluoroalkenylation of compounds with inert C(sp3)-H bonds.

Visible light photocatalytic decarboxylative monofluoroalkenylation of α-amino acids with: Gem -difluoroalkenes

α-Amino acids are among the most common biologically active molecules in nature, and their functionalization has attracted much attention. In this communication, a novel, efficient and general visible-light photocatalytic decarboxylative monofluoroalkenylation of N-protected α-amino acids with gem-difluoroalkenes is reported, affording the corresponding α-amino monofluoroalkenes which might find applications in medical chemistry and materials science. The reaction proceeded at room temperature with high efficiency and tolerance of various functional groups.