54245-33-9

Basic information

• Product Name: 3-bromonaphthalen-2-amine
• Synonyms: 3-bromonaphthalen-2-amine;3-Bromo-2-naphthalenamine;2-Amino-3-bromonaphthalene;2-NaphthalenaMine, 3-broMo-
• CAS NO: 54245-33-9
• Molecular Formula: C₁₀H₈BrN
• Molecular Weight: 222.08122
• EINECS: 259-043-0
• Mol File: 54245-33-9.mol
• Article Data: 2

Chemical Properties

• Melting Point: 168 °C
• Boiling Point: 345.5°Cat760mmHg
• Flash Point: 162.8°C
• Appearance: /
• Density: 1.563g/cm³
• Vapor Pressure: 6.12E-05mmHg at 25°C
• Refractive Index: 1.718
• Storage Temp.: 2-8°C(protect from light)
• PKA: 2.72±0.10(Predicted)
• CAS DataBase Reference: 3-bromonaphthalen-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-bromonaphthalen-2-amine(54245-33-9)
• EPA Substance Registry System: 3-bromonaphthalen-2-amine(54245-33-9)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 54245-33-9(Hazardous Substances Data)

Usage

General Description

3-Bromonaphthalen-2-amine is a synthetic chemical compound that belongs to the class of organic compounds known as naphthalenes. It has a specific molecular formula of C10H8BrN, which reveals the presence of bromine, nitrogen, carbon, and hydrogen elements in the compound. Because of this unique composition, it is used in a variety of chemical industries and in academic research environments for various purposes. Typically, it appears as a crystalline compound at room temperature, displaying minimal reactivity under normal conditions. As with any chemical, improper handling can potentially lead to harmful physical and health hazards, as outlined by its safety data sheets, thus the need to ensure safe handling, storage, and disposal in laboratory environments.

InChI:InChI=1/C10H8BrN/c11-9-5-7-3-1-2-4-8(7)6-10(9)12/h1-6H,12H2

Upstream product

• 54288-95-8 1,3-dibromonaphthalen-2-amine 
• 84605-00-5 10-bromo-1,2,3,4,5,6,7,8,13,13,14,14-dodecachloro-1,4,4a,4b,5,8,8a,12b-octahydro-11-nitro-1,4-5,8-dimethanotriphenylene 
• 7647-01-0 hydrogenchloride 
• 690244-08-7 1,3-dibromo-2-nitro-naphthalene 
• 64-19-7 acetic acid 
• 67116-33-0 2-bromo-3-nitronaphthalene 
• 107784-15-6 (3-bromo-[2]naphthyl)-carbamic acid ethyl ester 

Downstream Products

• 54245-34-0 3-Brom-2-Naphthonitril 
• 54288-98-1 3-Brom-2-benzylmercaptonaphthalin 
• 16278-49-2 3-Brom-2-benzylsulfonylnaphthalin 
• 59024-98-5 2-(3-Fluoro-naphthalen-2-ylmethyl)-benzoic acid 
• 59024-97-4 2-[1-(3-Fluoro-naphthalen-2-yl)-ethyl]-benzoic acid 
• 59024-96-3 2-(3-Fluor-2-naphthoyl)-benzoesaeure 
• 54245-35-1 3-Phenacyl-2-naphthoesaeure 
• 54245-36-2 3-Ethoxy-2-naphthoesaeure 
• 25799-29-5 1-[4-(3-Bromo-naphthalen-2-ylsulfanyl)-3-nitro-phenyl]-ethanone 
• 93259-31-5 N-(3-bromo-1-nitro-[2]naphthyl)-toluene-4-sulfonamide 
• 76411-66-0 2-hydrazinonaphtho<2,3-d>thiazole 
• 38824-47-4 2-Phenyl-1H-benzindol 
• 107784-18-9 2-(ethoxycarbonyl)amino-3-(2'-phenylethynyl)naphthalene 

Relevant articles and documents

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Relative binding affinity of carboxylate and its isosteres: Nitro, phosphate, phosphonate, sulfonate, and δ-lactone

Using the mono and ditopic receptors 1 and 2 (N-n-butyl-N′-p-tolylurea and 4,8-bis[((n-butylamino)carbonyl)amino]dibenz[b, i]acridan), the relative binding affinities of the title functional groups were determined to be ArOPO32- ≥ ArPO32- > ArCOO- ≥ ArP(OH)O2- > ArOP(OH)O2- > ArSO3- > δ-lactone > ArNO2. No evidence of hydrogen bonding of nitrobenzene to 1 was detected in either CDCl3 or DMSO-d6, but in CCl4, Kassoc = 180 M-1. Ditopic receptor 2 was designed as a receptor for meta-disubstituted aromatic substrates and binds some (isophthalate and 1,3-C6H4(P(OH)O2-)2) with high affinity (Kassoc > 104 M-1) in DMSO-d6. In contrast, the isosteric m-dinitrobenzene is not bound by 2 in that solvent, which further illustrates the relatively poor hydrogen bonding ability of nitro groups.