54080-90-9Relevant articles and documents
Novel synthetic route to 1-substituted cytosines
Ciszewski,Celewicz,Golankiewicz
, p. 777 - 779 (2007/10/02)
1-Alkylcytosines, cytidine and 2'-deoxy-5-methylcytidine were synthesized in good yields from appropriate 1-alkyluracils, uridine or thymidine derivatives by hydrogenation of 6-substituted tetrazolo[1,5-c]pyrimidin-5(6H)-ones 2 over 10% palladium on charcoal in methanol. Compounds 2 were obtained by the reaction of 1-substituted uracils 1 with sodium azide and phosphorus oxychloride in acetonitrile.