5402-60-8

Basic information

• Product Name: 2,6-Dimethylbenzyl chloride
• Synonyms: 1-CHLOROMETHYL-2,6-DIMETHYLBENZENE;2-CHLOROMETHYL-1,3-DIMETHYL-BENZENE;2,6-DIMETHYLBENZYL CHLORIDE;2-(Chloromethyl)-1,3-dimethylbenzene, 2-(Chloromethyl)-m-xylene;[(2,6-diMethylphenyl)Methyl]chloranuide
• CAS NO: 5402-60-8
• Molecular Formula: C₉H₁₁Cl
• Molecular Weight: 154.64
• Product Categories: Benzene derivatives
• Mol File: 5402-60-8.mol
• Article Data: 10

Chemical Properties

• Melting Point: 33-35°C
• Boiling Point: 70°C 5mm
• Flash Point: 33 °C
• Appearance: /
• Density: 1.033 g/cm³
• Vapor Pressure: 0.132mmHg at 25°C
• Refractive Index: 1.522
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2,6-Dimethylbenzyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Dimethylbenzyl chloride(5402-60-8)
• EPA Substance Registry System: 2,6-Dimethylbenzyl chloride(5402-60-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• RIDADR: 3261
• HazardClass: IRRITANT, LACHRYMATOR
• Hazardous Substances Data: 5402-60-8(Hazardous Substances Data)

Usage

General Description

2,6-Dimethylbenzyl chloride is a chemical compound with the formula C9H11Cl. It is a colorless to pale yellow liquid with a strong, pungent odor. This chemical is commonly used as an intermediate in the production of various pharmaceuticals, agrochemicals, and dyes. It acts as a key building block in the synthesis of other organic compounds, particularly in the manufacturing of insecticides and disinfectants. 2,6-Dimethylbenzyl chloride also exhibits some degree of toxicity and should be handled with caution in a well-ventilated environment. Overall, it serves a crucial role as a versatile chemical intermediate in a variety of industrial processes.

InChI:InChI=1/C9H11Cl/c1-7-4-3-5-8(2)9(7)6-10/h3-5H,6H2,1-2H3

Upstream product

• 62285-58-9 2,6-dimethylbenzyl alcohol 
• 7093-91-6 chloromethyl isocyanate 
• 108-38-3 m-xylene 
• 50-00-0 formaldehyd 
• 632-46-2 2,6-dimethylbenzoic acid 
• 1123-56-4 2,6-dimethylbenzaldehyde 
• 87-62-7 2,6-dimethylaniline 
• 608-28-6 2,6-dimethyliodobenzene 

Downstream Products

• 19289-31-7 3-<2,6-Dimethyl-benzyloxy>-3-methyl-acrylsaeureethylester 
• 1001096-12-3 C₂₄H₃₀NO₄P 
• 875769-60-1 (2,6-dichloro-3-nitropyridin-4-yl)-(2,6-dimethylbenzyl)amine 
• 403668-99-5 isopropyl 8-(2,6-dimethylbenzylamino)-2,3-dimethylimidazo[1,2-a]pyridine-6-carboxylate 
• 248920-23-2 methyl 2,3-dimethyl-8-(2,6-dimethylbenzylamino)-imidazo[1,2-a]pyridine-6-carboxylate 
• 212267-75-9 6-bromo-N-[(2,6-dimethylphenyl)methyl]-2,3-dimethylimidazo[1,2-a]pyridin-8-amine 
• 910777-50-3 6-bromo-N-[(2,6-dimethylphenyl)methyl]-2-methylimidazo[1,2-a]pyridin-8-amine 
• 259524-15-7 diethyl 8-(2,6-dimethylbenzylamino)imidazo[1,2-a]pyridine-2,3-dicarboxylate 
• 259524-11-3 ethyl 8-(2,6-Dimethylbenzylamino)-3,6-dimethylimidazo[1,2-a]pyridin-2-carboxylate 
• 259524-05-5 ethyl 8-(2,6-dimethylbenzylamino)-3-methylimidazo[1,2-a]pyridine-2-carboxylate 
• 200799-05-9 4-(2,6-dimethylbenzylamino)-2-methylbenzimidazole 
• 200799-06-0 4-(2,6-dimethylbenzyloxy)-2-methylbenzimidazole 
• 477573-09-4 5-(2,6-Dimethyl-phenylmethanesulfonyl)-1,3-dihydro-indol-2-one 
• 126328-93-6 2-Iodomethyl-1,3-dimethyl-benzene 

Relevant articles and documents

PROCESS FOR PREPARING 2,6-DIALKYLPHENYLACETIC ACIDS

The invention relates to a multi-stage process for preparing 2,6-dialkylphenylacetic acids of the general formula (I) by reacting 2,6-dialkylbromobenzenes with (1) magnesium, (2) a formamide, (3) an acid, (4) hydrogenation of the benzaldehyde obtained, (5

BENZODIAZEPINONE COMPOUNDS USEFUL IN THE TREATMENT OF SKIN CONDITIONS

The present invention provides a family of benzodiazepinone compounds and pharmaceutical compositions thereof. The present invention also provides methods of treating certain skin conditions, e.g., atopic dermatitis, rosacea, or psoriasis, by administering a benzodiazepinone and methods of reducing the proliferation of keratinocyte cells by exposing such cells to a benzodiazepinone.

COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS

Agents useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis are disclosed. Formula (I), wherein n is 1 or 2; m is 0 or 1; q is 0 or 1; t is 0 or 1; R5 is alkyl having from 1 to 3 carbon atoms; R9 is hydrogen, halo, alkyl having from 1 to 3 carbon atoms, or alkoxy having from 1 to 3 carbon atoms; A is phenyl, unsubstituted or substituted by 1 or 2 groups selected from: halo, alkyl having 1 or 2 carbon atoms, perfluoromethyl, alkoxy having 1 or 2 carbon atoms, and perfluoromethoxy; or cycloalkyl having from 3 to 6 ring carbon atoms wherein the cycloalkyl is unsubstituted or one or two ring carbons are independently mono-substituted by methyl or ethyl; or a 5 or 6 membered heteroaromatic ring having 1 or 2 ring heteroatoms selected from N, S and 0 and the heteroaromatic ring is covalently bound to the remainder of the compound of formula I by a ring carbon; and X is -CH2-, Q is -OR1and R1 is methyl or ethyl; or X is -CH2CR12R13- or - CH2CH(NHAc)-wherein each of R12 and R13is independently hydrogen or methyl, Q is OR1 and R1 is hydrogen or alkyl having from 1 to 7 carbon atoms; or X is -CH2CH2- and Q is NR10R1'wherein one of R10 and R11is hydrogen, alkyl having from 1 to 3 carbon atoms or hydroxy, and the other is hydrogen. Alternatively, when R1 is hydrogen, the biologically active agent can be a pharmaceutically acceptable salt of the compound of Formula (I).